Correlation of 19F-NMR spectra of halothane in rat tumor and non-tumor tissues with membrane alterations.
Biochim Biophys Acta
; 844(3): 346-51, 1985 Mar 21.
Article
em En
| MEDLINE
| ID: mdl-3871638
ABSTRACT
The membrane environments in normal and tumor rat tissue and the effect of hyperthermia thereon are studied with 19F-NMR spectroscopy of the general anesthetic halothane. Normal and tumor cell types are clearly differentiated by the halothane resonance. A hydrophobic environment prominent in tumor tissue is more sensitive to heat treatment than the corresponding environments of normal cells. Studies of extracted lipids suggest that this may be due in part to the considerable difference in lipid temperature response which exists between normal and kidney tumor cells.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Espectroscopia de Ressonância Magnética
/
Adenocarcinoma
/
Halotano
/
Hipertermia Induzida
/
Neoplasias Renais
Limite:
Animals
Idioma:
En
Revista:
Biochim Biophys Acta
Ano de publicação:
1985
Tipo de documento:
Article