Impact of anatomical liver resection for hepatocellular carcinoma in preventing early-phase local recurrence after surgery.
J Hepatobiliary Pancreat Sci
; 31(8): 513-527, 2024 Aug.
Article
em En
| MEDLINE
| ID: mdl-38803276
ABSTRACT
BACKGROUND:
The superiority of anatomical liver resection (AR) for localized hepatocellular carcinoma (HCC) over nonanatomical liver resection (NR) remains controversial. This study aimed to investigate the impact of AR in preventing local and early HCC recurrence.METHODS:
A total of 280 patients who underwent initial liver resection for solitary HCC ≤5 cm in diameter were categorized into the AR and NR groups and compared using propensity score matching analysis.RESULTS:
Between the matched pairs (n = 87 in each group), the incidence rates of local and early (recurrence within 2 years after surgery) recurrences in the AR group were significantly lower than those in the NR group (13.8% vs. 28.7%, p = .025; 20.7% vs. 35.6%, p = .028, respectively). The overall survival in the AR group was better than that in the NR group (median 13.4 vs. 7.6 years, p = .003). NR was among independent risk factors for early recurrence (odds ratio 1.98, 95% CI 1.1-3.6, p = .023) and prognostic factors for local recurrence (hazard ratio 2.44, 95% CI 1.4-4.4, p = .003).CONCLUSION:
AR is superior in controlling local and early recurrence postoperatively for solitary HCC ≤5 cm in diameter compared with NR.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Carcinoma Hepatocelular
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Pontuação de Propensão
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Hepatectomia
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Neoplasias Hepáticas
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Recidiva Local de Neoplasia
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
J Hepatobiliary Pancreat Sci
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Japão