Fulminant gangrene in transient cold agglutinemia associated with Escherichia coli infection.
Can Med Assoc J
; 132(3): 261-3, 1985 Feb 01.
Article
em En
| MEDLINE
| ID: mdl-3881156
ABSTRACT
Fulminant gangrene of the fingers, toes and nose developed in a 57-year-old woman with Escherichia coli pneumonia. Cryoglobulinemia was noted, and the cryoglobulin was identified as IgM-IgG with anti-I cold agglutinin activity. The cold agglutinins possessed potent lymphocytotoxic and monocytotoxic activity and weaker granulocytotoxic activity. Treatment with plasmapheresis, steroids and antibiotics led to complete clinical recovery, although amputation of several toes was necessary. The patient died 1 1/2 years later; the main findings at autopsy were chronic and acute pyelonephritis and acute bacterial endocarditis. This seems to be the first case of IgM-IgG cold agglutinemia occurring during the course of E. coli infection and the third case of fulminant gangrene complicating transient cold agglutinemia.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções por Escherichia coli
/
Gangrena
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Anemia Hemolítica Autoimune
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
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Humans
/
Middle aged
Idioma:
En
Revista:
Can Med Assoc J
Ano de publicação:
1985
Tipo de documento:
Article