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Sunflower Pollen-Derived Microspheres Selectively Absorb DNA for microRNA Detection.
Yang, Yao; Mou, Ziye; Liu, Qian; Wang, Bin; Luo, Chenjing; Xu, Yuhang; Huang, Qiuhong; He, Binfeng; Chang, Kai; Wang, Guansong; You, Zaichun; Qian, Hang.
Afiliação
  • Yang Y; Institute of Respiratory Diseases, Xinqiao Hospital, Chongqing Key Laboratory of Precision Medicine and Prevention of Major Respiratory Diseases, Third Military Medical University, Chongqing, 400037, China.
  • Mou Z; Department of General Practice, Xinqiao Hospital, Third Military Medical University., Chongqing, 400037, China.
  • Liu Q; Laboratory of Pharmacy and Chemistry, Laboratory of Tissue and Cell Biology, Lab Teaching & Management Center, Chongqing Medical University, Chongqing, 400016, China.
  • Wang B; Institute of Respiratory Diseases, Xinqiao Hospital, Chongqing Key Laboratory of Precision Medicine and Prevention of Major Respiratory Diseases, Third Military Medical University, Chongqing, 400037, China.
  • Luo C; Department of Pharmacy, The Second Affiliated Hospital of Army Medical University, Chongqing, 400037, China.
  • Xu Y; Institute of Respiratory Diseases, Xinqiao Hospital, Chongqing Key Laboratory of Precision Medicine and Prevention of Major Respiratory Diseases, Third Military Medical University, Chongqing, 400037, China.
  • Huang Q; Department of General Practice, Xinqiao Hospital, Third Military Medical University., Chongqing, 400037, China.
  • He B; Department of General Practice, Xinqiao Hospital, Third Military Medical University., Chongqing, 400037, China.
  • Chang K; School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China.
  • Wang G; Institute of Respiratory Diseases, Xinqiao Hospital, Chongqing Key Laboratory of Precision Medicine and Prevention of Major Respiratory Diseases, Third Military Medical University, Chongqing, 400037, China.
  • You Z; Department of General Practice, Xinqiao Hospital, Third Military Medical University., Chongqing, 400037, China.
  • Qian H; Institute of Respiratory Diseases, Xinqiao Hospital, Chongqing Key Laboratory of Precision Medicine and Prevention of Major Respiratory Diseases, Third Military Medical University, Chongqing, 400037, China.
Chembiochem ; 25(20): e202400249, 2024 Oct 16.
Article em En | MEDLINE | ID: mdl-38819725
ABSTRACT
Herein, we report the finding that a naturally sunflower pollen-derived microspheres (HSECs) with hierarchical structures can selectively absorb polyC and polyA with high efficiency and affinity. HSECs exhibit the capability to selectively absorb polyC and polyA ssDNA under neutral and acidic conditions. It has been observed that the presence of metal cations, specifically Ca2+, enhances the absorption efficiency of HSECs. Mechanically, this absorption phenomenon can be attributed to both electrostatic interactions and cation-π interactions. Such an appealing property enables the functionalization of HSECs for broad potential biomedical applications, such as microRNA detection.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pólen / MicroRNAs / Helianthus / Microesferas Idioma: En Revista: Chembiochem Assunto da revista: BIOQUIMICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pólen / MicroRNAs / Helianthus / Microesferas Idioma: En Revista: Chembiochem Assunto da revista: BIOQUIMICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China