Severe hepatic cholestasis after treatment with amoxicillin/clavulanic acid.
Ugeskr Laeger
; 186(21)2024 May 20.
Article
em Da
| MEDLINE
| ID: mdl-38847310
ABSTRACT
Amoxicillin/clavulanate is a commonly used antibiotic. Though relatively rare, amoxicillin/clavulanate carries the highest incidence of idiosyncratic drug-induced liver disease. This case report presents an 80-year-old woman treated for simple respiratory tract infection with amoxicillin/clavulanate who was subsequently hospitalized with malaise and icterus and a biochemical cholestatic pattern with high alkaline phosphatase and bilirubin. Diagnostically challenging, ultimately, liver biopsy revealed drug-induced liver injury with a fatal course after attempt of supportive, symptomatic treatment.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Combinação Amoxicilina e Clavulanato de Potássio
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Doença Hepática Induzida por Substâncias e Drogas
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Antibacterianos
Limite:
Aged80
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Female
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Humans
Idioma:
Da
Revista:
Ugeskr Laeger
Ano de publicação:
2024
Tipo de documento:
Article