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Chlormequat chloride induces hepatic steatosis by promoting mTOR/SREBP1 mediated lipogenesis via AMPK inhibition.
Kang, Chengping; Xiao, Qianqian; Wang, Xiaoxia; Guo, Wanqian; Zhang, Haoran; Yuan, Lilan; Zhao, Zhe; Hao, Weidong.
Afiliação
  • Kang C; Department of Toxicology, School of Public Health, Peking University Health Science Center, Beijing, 100191, PR China; Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety, Beijing, 100191, PR China.
  • Xiao Q; Department of Toxicology, School of Public Health, Peking University Health Science Center, Beijing, 100191, PR China; Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety, Beijing, 100191, PR China.
  • Wang X; Department of Toxicology, School of Public Health, Peking University Health Science Center, Beijing, 100191, PR China; Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety, Beijing, 100191, PR China.
  • Guo W; Department of Toxicology, School of Public Health, Peking University Health Science Center, Beijing, 100191, PR China; Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety, Beijing, 100191, PR China.
  • Zhang H; Department of Toxicology, School of Public Health, Peking University Health Science Center, Beijing, 100191, PR China; Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety, Beijing, 100191, PR China.
  • Yuan L; Department of Toxicology, School of Public Health, Peking University Health Science Center, Beijing, 100191, PR China; Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety, Beijing, 100191, PR China.
  • Zhao Z; Department of Toxicology, School of Public Health, Peking University Health Science Center, Beijing, 100191, PR China; Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety, Beijing, 100191, PR China.
  • Hao W; Department of Toxicology, School of Public Health, Peking University Health Science Center, Beijing, 100191, PR China; Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety, Beijing, 100191, PR China. Electronic address: whao@bjmu.edu.cn.
Food Chem Toxicol ; 190: 114790, 2024 Aug.
Article em En | MEDLINE | ID: mdl-38849044
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Clormequat / Proteína de Ligação a Elemento Regulador de Esterol 1 / Lipogênese / Proteínas Quinases Ativadas por AMP / Fígado Gorduroso / Serina-Treonina Quinases TOR Limite: Animals / Humans / Male Idioma: En Revista: Food Chem Toxicol Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Clormequat / Proteína de Ligação a Elemento Regulador de Esterol 1 / Lipogênese / Proteínas Quinases Ativadas por AMP / Fígado Gorduroso / Serina-Treonina Quinases TOR Limite: Animals / Humans / Male Idioma: En Revista: Food Chem Toxicol Ano de publicação: 2024 Tipo de documento: Article