Prevalence of Listeria monocytogenes in Milk and Dairy Product Supply Chains: A Global Systematic Review and Meta-analysis.

ABSTRACT

Listeria monocytogenes, one of the main foodborne pathogens, is commonly found in milk and dairy products. This study aimed to estimate the presence of L. monocytogenes in milk and dairy product supply chains using a meta-analysis based on PubMed, Embase, Web of Science, and Scopus databases. A total of 173 studies were included in this meta-analysis. The pooled prevalence in the supply chain environment was 8.69% (95% confidence interval [CI] 5.30%-12.78%), which was higher than that in dairy products (4.60%, 95% CI 1.72%-8.60%) and milk products (2.93%, 95% CI 2.14%-3.82%). Subgroup analysis showed that L. monocytogenes prevalence in raw milk (3.44%, 95% CI 2.61%-4.28%) was significantly higher than in pasteurized milk (0.60%, 95% CI 0.00%-2.06%). The highest prevalence of L. monocytogenes in milk and dairy products was observed in North America (5.27%, 95% CI 2.19%-8.35%) and South America (13.54%, 95% CI 3.71%-23.37%). In addition, studies using culture and molecular methods (5.17%, 95% CI 2.29%-8.06%) had higher prevalence than other detection methods. Serogroup 1/2a and 3a (45.34%, 95% CI 28.74%-62.37%), serogroup 1/2b and 3b (14.23%, 95% CI 6.05%-24.24%), and serogroup 4b/4e (13.71%, 95% CI 6.18%-22.83%) were dominant in these studies. The results of this study provide a better understanding of the prevalence of L. monocytogenes in milk and dairy product supply chains and suggest a potential foodborne pathogen burden.