Inhibition of METTL4: Targeting a Methyltransferase that Alleviates Heart Failure by Modulating Excess N6-Methyladenine in Mitochondrial DNA.

Wang, Jiaqi; Spanos, Michail; Bei, Yihua

Wang, Jiaqi; Spanos, Michail; Bei, Yihua.

Afiliação

Wang J; Shanghai Applied Radiation Institute, School of Environmental and Chemical Engineering, Shanghai University, Shanghai, 200444, China.
Spanos M; Institute of Cardiovascular Sciences, Shanghai Engineering Research Center of Organ Repair, Joint International Research Laboratory of Biomaterials and Biotechnology in Organ Repair (Ministry of Education), School of Life Science, Shanghai University, Shanghai, 200444, China.
Bei Y; Cardiovascular Division of the Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.

J Cardiovasc Transl Res ; 2024 Jul 11.

Article em En | MEDLINE | ID: mdl-38992315

Palavras-chave

6 mA; Heart failure; METTL4; Mitochondrial dysfunction; mtDNA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Cardiovasc Transl Res Assunto da revista: ANGIOLOGIA / CARDIOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China

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