Ethnobotany, phytochemistry, pharmacology and quality control of Peucedanum decursivum (Miq.) Maxim: A critical review.
J Ethnopharmacol
; 334: 118542, 2024 Nov 15.
Article
em En
| MEDLINE
| ID: mdl-38992404
ABSTRACT
ETHNOPHARMACOLOGICAL RELEVANCE Dried roots of Peucedanum decursivum, a traditional Chinese medicine (TCM), has historically respiratory diseases such as cough, thick phlegm, headache, fever, and gynecological diseases, rheumatoid arthritis, and nasopharyngeal carcinoma. AIM OF THE STUDY Made an endeavor to evaluate the research trajectory of P. decursivum, comprehensively discern its developmental status, and offer a guideline for future investigations. MATERIALS AND METHODS:
A meticulous search of literatures and books from 1955 to 2024 via databases like PubMed, Web of Science and CNKI was conducted, including topics and keywords of " P. decursivum" "Angelica decursivum" and "Zihua Qianhu".RESULTS:
P. decursivum and its prescriptions have traditionally been used for treating phlegm-heat cough, wind-heat cough, gastrointestinal diseases, pain relief and so on. It contains 234 identified compounds, encompassing coumarins, terpenes, volatile oils, phenolic acids, fatty acids and derivatives. It exhibits diverse pharmacological activities, including anti-asthmatic, anti-inflammatory, antioxidant effects, anti-hypertensive, anti-diabetic, anti-Alzheimer, and anti-cancer properties, primarily attributed to coumarins. Microscopic identification, HPLC fingerprinting, and bioinformatics identification are the primary methods currently used for the quality control.CONCLUSION:
P. decursivum demonstrates anti-asthmatic, anti-inflammatory, and antioxidant effects, aligning with its traditional use. However, experimental validation of its efficacy against phlegm and viruses is needed. Additionally, analgesic effects mentioned in historical texts lack modern pharmacological studies. Numerous isolated compounds exhibit highly valuable medicinal properties. Future research can delve into exploring these substances further. Rigorous of heavy metal contamination, particularly Cd and Pb, is necessary. Simultaneously, investigating its pharmacokinetics and toxicity in humans is crucial for the safety.Palavras-chave
(+)-trans-decursidinol (PubChem CID: 10355323); (1S,15S)-2,4-Bis(1,1-Dimethylethyl)-phenol (PubChem CID: 7311); (1α,4αß,8aα)-1-isopropanol-4a-methyl-8-methylenedecahydronaphthalene (PubChem CID: 162859556); (3'R,4'R)-3'-angeloyloxy-4'-senecioyloxy-3',4'-dihydroseselincalipteryxin (PubChem CID: 1119128); (9R,10R)-9-Acetoxy-8,8-dimethyl-9,10-dihydro -2H,8H-benzo[1,2-b:3,4-b']dipyran-2-one-10-yl-ester (PubChem CID: 636714); (E)-2-Octenal (PubChem CID: 5283324); (Z)-2-decenal (PubChem CID: 5354834); (−)-Spathulenol (PubChem CID: 13854255); (−)-ß-Elemene (PubChem CID: 6918391); 1-(1,4-Dimethyl-3-cyclohexen-1-yl)-ethanon (PubChem CID: 65289); 1-Decanol (PubChem CID: 8174); 1-Ethenyl-1-methyl-2,4-bis(1-methylethenyl)-cyclohexane (PubChem CID: 10583); 1-Ethyl-4-isopropylbenzene (PubChem CID: 20197); 1-Menthone (PubChem CID: 26447); 1-Pentadecanol (PubChem CID: 12397); 13-Tetradecenal (PubChem CID: 522841); 2,2,3,3-Tetramethylbutane (PubChem CID: 11675); 2,3,3-Trimethyloctane (PubChem CID: 537321); 2,4-Decadienal (PubChem CID: 5283349); 2,4-Dimethyl hexane (PubChem CID: 11511); 2,6,6-Trimethyl-bicyclo [3.1.1] heptan-3-one (PubChem CID: 86707); 2,7-Dimethyl-1,3,7-octatriene (PubChem CID: 5367594); 2-Butenoic acid-3-methyl-3-methylbutyl ester (PubChem CID: 92570); 2-Carene (PubChem CID: 78249); 2-Hydroxy-3-(3-methyl-2-butenyl)-7H-furo[3,2-g][1]benzopyran-7-one (PubChem CID: 101940767); 2-Methoxy cinnamaldehyde (PubChem CID: 641298); 2-Methoxy-4-vinylphenol (PubChem CID: 332); 2-Methyl-decane (PubChem CID: 23415); 2-Nonanone (PubChem CID: 13187); 2-Pentylfuran (PubChem CID: 19602); 3-Carene (PubChem CID: 26049); 3-Cyclopentene-1-carbaldehyde (PubChem CID: 5314123); 3-Furaldehyde (PubChem CID: 10351); 3R,8S-falcarindiol (PubChem CID: 5281148); 4-(1-Methylethyl)-cyclohexanol (PubChem CID: 20739); 4-Carene (PubChem CID: 21674939); 4-Hydroxybenzoic acid (PubChem CID: 135); 4-Isopropyl-2-cyclohexenone (PubChem CID: 92780); 4-Terpineol (PubChem CID: 11230); 4'-hydroxy-3'-methylacetophenone (PubChem CID: 70135); 5-Hydroxymethylfurfural (PubChem CID: 237332); 5-Methylfurfural (PubChem CID: 12097); 6,6-Dimethylbicyclo[3.1.1] heptan-2-one (PubChem CID: 32735); 6-Hydroxy-5-methyl-6-vinyl-bicyclo [3.2.0] heptan-2-one (PubChem CID: 566074); 7,9,12-Octadecadienoic acid methyl ester (PubChem CID: 3931); 8-(2-Hydroxypropan-2-yl)-2-oxo-2H,8H,9H-furo[2,3-h]chromen-9-yl 3-methylbut-2-enoate (PubChem CID: 75169283); AD-II (andelin) (PubChem CID: 101306694); Acetophenone (PubChem CID:7410); Alsaticol (PubChem CID: 102452703); Angelicin (isopsoralen) (PubChem CID: 10658); Apiole (PubChem CID: 10659); Bakuchicin (PubChem CID: 3083848); Berbenone (PubChem CID: 12444758); Bergapten (PubChem CID: 2355); Bicyclo[13.1.0]hexadecan-2-one (PubChem CID: 13760785); Borneol (PubChem CID: 6552009); Bornyl acetate (PubChem CID: 6448); Camphene (PubChem CID: 6616); Caryophyllene (PubChem CID: 5281515); Caryophyllene oxide (PubChem CID: 1742210); Cinnamaldehyde (PubChem CID: 6428995); Cinnamyl alcohol (PubChem CID: 5315892); Columbianadin (PubChem CID: 6436246); Copaene (PubChem CID: 19725); Coumarin (PubChem CID: 323); Crocatone (PubChem CID: 177099); Cubenol (PubChem CID: 11770062); Cuparene (PubChem CID: 86895); Cycloisosativene (PubChem CID: 519960); D-limonene (PubChem CID: 440917); Daucosterol (PubChem CID: 5742590); Decuroside I (PubChem CID: 122169321); Decuroside III (PubChem CID: 442125)IV (PubChem CID: 75368779); Decuroside V (PubChem CID: 10025355); Decursidate (PubChem CID: 102004630); Decursidin (PubChem CID: 15521791); Decursin (PubChem CID: 442126); Decursinol angelate (PubChem CID: 776123); Decursitin A (PubChem CID: 21581508); Decursitin B (Xanthalin) (PubChem CID: 21581509); Decursitin D (PubChem CID: 122169319); Decursitin F (PubChem CID: 5320881); Deltoin (PubChem CID: 6183350); Demethylsuberosin (PubChem CID: 5316525); Di-n-pentyl phthalate (PubChem CID: 8561); Dibutyl phthalate (PubChem CID: 3026); Edulisin II (PubChem CID: 58488747); Edultin (PubChem CID: 5317013); Elixene (PubChem CID: 94254); Eremophilene (PubChem CID: 12309744); Ethnobotany; Ethyl-cyclohexane (PubChem CID: 15504); Ethyl-cyclopentane (PubChem CID: 15431); Eudesma-4(14),11-diene (PubChem CID: 6432497); Farnesol (PubChem CID: 3327); Ferulic acid (PubChem CID: 445858); Geranyl butyrate (PubChem CID: 5355856); Geranyl isovalerate (PubChem CID: 5362830); Germacrene D (PubChem CID: 5317570); Heptaldehyde (PubChem CID: 8130); Hexadecane (PubChem CID: 11006); Hexanal (PubChem CID: 6184); Humulene oxide II (PubChem CID: 129317183); Imperatorin (PubChem CID: 10212); Isobergapten (PubChem CID: 68082); Isoimperatorin (PubChem CID: 68081); Isoledene (PubChem CID: 530426); Isononane (PubChem CID: 18591); Isopimpinellin (PubChem CID: 68079); Isothymol methyl ether (PubChem CID: 161716); Juniper camphor (PubChem CID: 521214); Libanoridin (PubChem CID: 161409); Linoleic acid (PubChem CID: 5280450); Longifolen (PubChem CID: 289151); Methoxy-5-prenyloxycoumarin (PubChem CID:15108314); Methy-cyclohexane (PubChem CID: 7962); Methyl cinnamate (PubChem CID: 637520); Methyl oleate (PubChem CID: 5364509); Methyl palmitate (PubChem CID: 8181); Methylparaben (PubChem CID: 7456); Myristic acid (PubChem CID: 11005); Myrtenal (PubChem CID: 61130); N-henicosane (PubChem CID: 12403); Nerolidol (PubChem CID: 8888); Nodakenetin (Marmesin) (PubChem CID: 26305); Nodakenin (PubChem CID: 73191); Nonanal (PubChem CID: 31289); Nonane (PubChem CID: 8141); Norbornane (PubChem CID: 9233); Nuttallin (PubChem CID: 12313622); Octanal (PubChem CID: 454); Oleic acid (PubChem CID: 445639); Ostenol (PubChem CID: 5320318); Osthole (PubChem CID: 10228); Ostruthin (PubChem CID: 5281420); Oxacyclotridecan-2-one (PubChem CID: 70354); Palmitic acid (PubChem CID: 985); Palmitoleic acid (PubChem CID: 445638); Pd-C-II (PubChem CID: 163106961); PdCI (PubChem CID: 49818880); Pentadecane (PubChem CID: 12391); Pentadecanoic acid (PubChem CID: 13849); Peucedanocoumarin II (PubChem CID: 5434471); Peucedanum decursivum (Miq.) Maxim; Peujaponisinol A (PubChem CID: 162927134); Peujaponisinol B (PubChem CID: 51669194); Pharmacology; Phellandral (PubChem CID: 89488); Phytochemistry; Pimpinellin (PubChem CID: 4825); Praeruptorin B (PubChem CID: 5319259); Protocatechualdehyde (PubChem CID: 8768); Psoralen (PubChem CID: 6199); Qianhucoumarin E (PubChem CID: 131676021); Quality control; Sabinaketone (PubChem CID: 92784); Sabinene (PubChem CID: 18818); Scopoletin (PubChem CID: 5280460); Selinidin (PubChem CID: 668081); Senkyunolide H (PubChem CID: 10036567); Solasonine (PubChem CID: 119247); Spathulenol (PubChem CID: 92231); Sphondin (PubChem CID: 108104); Squalene (PubChem CID: 638072); Suberosin (PubChem CID: 68486); T-Muurolol (PubChem CID: 3084331); T-cadinol (PubChem CID: 160799); Tanshinone â
¡A (PubChem CID: 114917); Terpene polychlorinates (PubChem CID: 22833294); Terpinene (PubChem CID: 7461); Terpinolene (PubChem CID: 11463); Tetradecanal (PubChem CID: 31291); Thujopsene (PubChem CID: 442402); Thymohydroquinone dimethyl ether (PubChem CID: 95779); Thymol methyl ether (PubChem CID: 14104); Umbelliferone (PubChem CID: 5281426); Umbelliferone 6-carboxylic acid (PubChem CID: 14189622); Undecane (PubChem CID: 14257); Vanillic acid (PubChem CID: 8468); Vanillin (PubChem CID: 1183); Viridiflorol (PubChem CID: 11996452); Widdrol (PubChem CID: 94334); Xanthotoxin (PubChem CID: 4114); Xanthyletin (PubChem CID: 65188); Z-Ligustilide (PubChem CID: 5319022); cis-9-Octadecenal (PubChem CID: 5364492); cis-Verbenol (PubChem CID: 61126); cis-α-Bisabolene (PubChem CID: 91753574); m-Cymene (PubChem CID: 10812); m-cresol (PubChem CID: 342); o-Cymene (PubChem CID: 10703); p-Cymen-8-ol (PubChem CID: 14529); p-Menthan-1-ol (PubChem CID: 89437); p-cis-Ocimene (PubChem CID: 5320250); trans-2-Decenal (PubChem CID: 5283345); trans-Carveol (PubChem CID: 94221); trans-Cinnamaldehyde (PubChem CID: 637511); α-Guaiene (PubChem CID: 5317844); α-Muurolene (PubChem CID: 12306047); α-Phellandrene (PubChem CID: 7460); α-Pinene (PubChem CID: 6654); α-Terpinene (PubChem CID: 7462); α-Yalangene (PubChem CID: 442409); ß-Bisabolene (PubChem CID: 10104370); ß-Bourbonene (PubChem CID: 62566); ß-Fenchol (PubChem CID: 6973643); ß-Humulene (PubChem CID: 5318102); ß-Myrcene (PubChem CID: 31253); ß-Phellandrene (PubChem CID: 11142); ß-Pinene (PubChem CID: 14896); ß-Sesquiphellandrene (PubChem CID: 519764); ß-Sitosterol (PubChem CID: 222284); ß-Thujene (PubChem CID: 520384); ß-trans-Ocimene (PubChem CID: 18756); γ-(−)-Verbenone (PubChem CID: 92874)
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Controle de Qualidade
/
Etnobotânica
/
Apiaceae
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Etnofarmacologia
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Compostos Fitoquímicos
Limite:
Animals
/
Humans
Idioma:
En
Revista:
J Ethnopharmacol
Ano de publicação:
2024
Tipo de documento:
Article