Central nervous system prophylaxis in large B-cell lymphoma: A British Society for Haematology Good Practice Paper.

Wilson, Matthew R; Cwynarski, Kate; Eyre, Toby A; Smith, Jeffery; Chaganti, Sridhar; Fox, Christopher P; McKay, Pamela

Wilson, Matthew R; Cwynarski, Kate; Eyre, Toby A; Smith, Jeffery; Chaganti, Sridhar; Fox, Christopher P; McKay, Pamela.

Afiliação

Wilson MR; Beatson West of Scotland Cancer Centre, Glasgow, UK.
Cwynarski K; University College Hospital, London, UK.
Eyre TA; Oxford University Hospitals NHS Trust, Churchill Cancer Centre, Oxford, UK.
Smith J; Clatterbridge Cancer Centre, Liverpool, UK.
Chaganti S; Centre for Clinical Haematology, Queen Elizabeth Hospital, Birmingham, UK.
Fox CP; School of Medicine, University of Nottingham, Nottingham, UK.
McKay P; Beatson West of Scotland Cancer Centre, Glasgow, UK.

Br J Haematol ; 2024 Aug 11.

Article em En | MEDLINE | ID: mdl-39128894

ABSTRACT

ABSTRACT

This Good Practice Paper provides recommendations for the baseline investigation, risk stratification and use of prophylactic interventions for patients with large B-cell lymphoma at risk of central nervous system relapse. Recent evidence which has questioned the role of high-dose methotrexate in this clinical scenario is discussed in detail.

Palavras-chave

CNS prophylaxis; CNS relapse; diffuse large Bcell lymphoma; highdose methotrexate

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Br J Haematol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google