The Cronkhite-Canada syndrome: an ultrastructural study of pathogenesis.
J Clin Pathol
; 38(3): 271-6, 1985 Mar.
Article
em En
| MEDLINE
| ID: mdl-3973050
ABSTRACT
Electron microscopical and cytochemical studies of intestinal biopsies from a patient with typical features of the Cronkhite-Canada syndrome show that the primary process affects the crypts. This results in cystic dilatation associated with expansion and focal degeneration of the crypt compartment of the intestinal epithelium. The villous epithelium compartment is reduced but ultrastructurally normal. Inflammation and oedema of the lamina propria follows from leakage of mucin through breaks in the abnormal crypts.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pólipos
/
Alopecia
/
Neoplasias Gastrointestinais
/
Doenças da Unha
Tipo de estudo:
Etiology_studies
Limite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
J Clin Pathol
Ano de publicação:
1985
Tipo de documento:
Article