[Influence of chlormadinone acetate on hypothalamic differentiation in male rats]. / Einfluss von Chlormadinonazetat auf die Hypothalamusdifferenzierung männlicher Ratten.
Acta Biol Med Ger
; 26(1): 105-14, 1971.
Article
em De
| MEDLINE
| ID: mdl-4102815
ABSTRACT
PIP The effect of chlormadinone acetate on adult male rats during the hypothalamic differentiation phase was studied. Psychic intersexuality with increased male and increased female sexual behavior was observed both before and after postpuberal castration and sex hormone replacement. Organ weights of testes, seminal vesicles, and ventral prostrates were normal, but penis and adrenal gland weights were significantly smaller. Body growth was also significantly reduced compared with control animals. The effects of chlormadinone acetate on androgen-dependent brain differentiation are discussed and compared with analogous effects of cyproterone acetate and orchidectomy.^ieng
Palavras-chave
Animals, Laboratory; Castration; Chlormadinone Acetate--side effects; Clinical Research; Contraception; Contraceptive Agents, Female--side effects; Contraceptive Agents, Progestin--side effects; Contraceptive Agents--side effects; Family Planning; Research Methodology; Surgery; Treatment; Urogenital Surgery
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Acetato de Clormadinona
/
Hipotálamo
Limite:
Animals
Idioma:
De
Revista:
Acta Biol Med Ger
Ano de publicação:
1971
Tipo de documento:
Article