Abnormal mast cell granules in the beige (Chédiak-Higashi syndrome) mouse.
J Histochem Cytochem
; 23(2): 117-22, 1975 Feb.
Article
em En
| MEDLINE
| ID: mdl-46876
ABSTRACT
Mast cells of beige (C57BL/6J) (bg-j/bg-j) mice were examined histochemically and ultrastructurally. Mast cell granules in the beige mice were markedly enlarged and irregular in shape. Granule contents stained uniformly with acidified toluidine blue, but with ruthenium red and Alcian Blue-safranin, two components were evident. The rims of the abnormal granules stained with ruthenium red and with Alcian Blue; the centers of the granules were clear with ruthenium red and stained with safranin. Mast cell granules thus represent another abnormal organelle in the Chédiak-Higashi syndrome.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome de Chediak-Higashi
/
Grânulos Citoplasmáticos
/
Mastócitos
Limite:
Animals
Idioma:
En
Revista:
J Histochem Cytochem
Assunto da revista:
HISTOCITOQUIMICA
Ano de publicação:
1975
Tipo de documento:
Article