[Effect of trichlorfon on the blood resorption and elimination of radioactive vitamin B1 in cocks]. / Vliianie na trikhlorfona vurkhu rezorbtsiiata i eliminiraneto na radioaktiven vitamin B1 ot kruvta na petli.

ABSTRACT

Experimental studies on the effect of trichlorphon (neguvon) on the rate of vitamin B1 resorption in the alimentary tract and elimination by the blood in 12 cocks were carried out. Oral or intravenous application of 35S thiamin in the form of hypotonic and physiological solution was used for the previously treated per os with a neguvon water solution (40 mg/kg weight) cocks. As check the same cocks were treated three weeks before trichlorphon application by the radioindicator only. The birds' blood plasma was radiometrically studied (imp/min) after the "thin layer" method. It was established that as a result of trichlorphon solution treatment the radioactive vitamin B1 was immediately resorbed by the alimentary tract and its elimination by cock blood was reduced. The factors taking part in the mechanism of the observed phenomena are discussed.