Chemistry of proton abstraction by glycolytic enzymes (aldolase, isomerases and pyruvate kinase).
Philos Trans R Soc Lond B Biol Sci
; 293(1063): 131-43, 1981 Jun 26.
Article
em En
| MEDLINE
| ID: mdl-6115413
ABSTRACT
Intermediates have been synthesized that are rapidly utilized by triose phosphate isomerase, yeast aldolase and pyruvate kinase. In each case the compounds have the properties of an enol expected for a stepwise proton transfer mechanism. Apparently the apparatus required for doing this chemistry is sufficiently unique for a large measure of structural homology to have been imposed upon the enzymes of this class during evolution.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Piruvato Quinase
/
Triose-Fosfato Isomerase
/
Carboidratos Epimerases
/
Frutose-Bifosfato Aldolase
Idioma:
En
Revista:
Philos Trans R Soc Lond B Biol Sci
Ano de publicação:
1981
Tipo de documento:
Article