Radioimmunoassay for human pancreatic secretory trypsin inhibitor: measurement of serum pancreatic secretory trypsin inhibitor in normal subjects and subjects with pancreatic diseases.
Clin Chim Acta
; 103(2): 135-43, 1980 Apr 25.
Article
em En
| MEDLINE
| ID: mdl-6154549
ABSTRACT
A reliable radioimmunoassay (RIA) for human pancreatic secretory trypsin inhibitor (PSTI) has been developed. The method is highly sensitive (0.4 ng/ml), reproducible and specific. A good parallel relationship was observed between the standard curve and dilution curves for serum and urine. The PSTI bound to trypsin-alpha 2-macroglobulin complexes was found not to be immunoreactive, whereas a part of the psti-trypsin complex was immuno-reactive. In healthy individuals, serum PSTI level ranged from 5.4 ng/ml to 16.0 ng/ml, the average being 11.3 ng/ml (S.D. +/- 2.7). Elevated values were observed in patients with acute pancreatitis (highest value 3200 ng/ml), and in some patients with chronic relapsing pancreatitis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Suco Pancreático
/
Pancreatite
/
Inibidor da Tripsina Pancreática de Kazal
/
Inibidores da Tripsina
Limite:
Adult
/
Animals
/
Humans
Idioma:
En
Revista:
Clin Chim Acta
Ano de publicação:
1980
Tipo de documento:
Article