Hypogammaglobulinemia and Nocardia brain abscesses.
Neurosurgery
; 1(3): 297-9, 1977.
Article
em En
| MEDLINE
| ID: mdl-615978
ABSTRACT
The host defense responses to Nocardia asteroides are not known. We have investigated a patient with common variable adult onset hypogammaglobulinemia who developed fatal disseminated nocardiosis. The patient had low levels of serum immunoglobulins; the total lymphocyte count was normal as were the percentages of circulating T and B cells. Transmission electron microscopic studies demonstrated typical N. asteroides within the brain parenchyma and nonspecific inflammatory changes in the central nervous system. The findings suggest that humoral immunity may play a major role in the host defense of patients with this disease.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Abscesso Encefálico
/
Agamaglobulinemia
/
Nocardiose
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Neurosurgery
Ano de publicação:
1977
Tipo de documento:
Article