Reduced tissue content of vasoactive intestinal peptide in aganglionic colon of Hirschsprung's disease.
Am J Surg
; 141(2): 243-4, 1981 Feb.
Article
em En
| MEDLINE
| ID: mdl-6161549
ABSTRACT
The colonic tissue content of immunoreactive vasoactive intestinal peptide was measured in four children with histologically proven Hirschsprung's disease. The concentration of vasoactive intestinal peptide was lower in the aganglionic bowel than in nearby normal bowel. Similar results have been described for another gastrointestinal peptide substance P. Abnormalities of peptidergic control may contribute to the motility disorder of congenital aganglionic colon.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peptídeo Intestinal Vasoativo
/
Colo
/
Hormônios Gastrointestinais
/
Megacolo
Limite:
Child
/
Humans
Idioma:
En
Revista:
Am J Surg
Ano de publicação:
1981
Tipo de documento:
Article