Hepatitis B virus and cigarette smoking: risk factors for hepatocellular carcinoma in Hong Kong.
Cancer Res
; 42(12): 5246-8, 1982 Dec.
Article
em En
| MEDLINE
| ID: mdl-6291750
ABSTRACT
One hundred seven Chinese patients with primary hepatocellular carcinoma (PHC) were compared with 107 hospital controls for the presence of hepatitis B surface antigen and smoking, drinking, and dietary habits. Eighty-two % of PHC cases were hepatitis B surface antigen positive compared to 18% of controls (relative risk, 21.3; 95% confidence limits, 10.1 and 45.9). Prior history of jaundice was significantly related to PHC, independent of hepatitis B surface antigen status. There was a significant association between cigarette smoking and PHC negative for hepatitis B surface antigen. The relative risk of hepatitis B surface antigen-negative PHC for heavy smokers (20 + cigarettes/day) was 3.3 compared to light smokers and nonsmokers (95% confidence limits, 1.0 and 13.4). Our data indicated that infection by the hepatitis B virus and cigarette smoking were independent risk factors for PHC.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fumar
/
Carcinoma Hepatocelular
/
Antígenos de Superfície da Hepatite B
/
Neoplasias Hepáticas
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
Cancer Res
Ano de publicação:
1982
Tipo de documento:
Article