Heterogeneity in the phenotypic profile of cerebriform cells from a patient with Sézary syndrome.
Tumori
; 70(6): 507-11, 1984 Dec 31.
Article
em En
| MEDLINE
| ID: mdl-6531793
ABSTRACT
This paper reports the results of a series of light and electron microscopic, cytochemical, immunologic and cytogenetic investigations performed in a patient with Sézary syndrome. Fifty-two percent of the cerebriform cells were OKIa-1 positive and 55% were acid alpha-naphthyl-acetate esterase (ANAE) negative. Since activated T-lymphocytes are known to lose their peculiar ANAE activity while acquiring Ia-like antigens, it is conceivable that the ANAE-negative and OKIa-1-positive cells represent an in vivo activated subset. Thus, it appears that a typical Sézary cell population from a given individual can exhibit heterogeneous phenotypic profiles.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome de Sézary
Limite:
Aged
/
Female
/
Humans
Idioma:
En
Revista:
Tumori
Ano de publicação:
1984
Tipo de documento:
Article