[Relation between the HLA system and the development of asbestosis fibrosis in a group of workers exposed to asbestos]. / Etude des relations entre le système HLA et l'apparition d'une fibrose asbestosique dans un groupe de travailleurs exposés à l'aminate.
Poumon Coeur
; 39(6): 283-6, 1983.
Article
em Fr
| MEDLINE
| ID: mdl-6664943
ABSTRACT
The various studies which have dealt up to the present with a possible relationship between asbestosis and HLA groups have led to differing conclusions. The present study evaluated this relationship by comparison of 57 workers with asbestosis confirmed radiologically (minimum S1 type opacities) and functionally (VC and/or DuaCO less than 88%) with 58 controls from the same population. In a second phase, statistical analysis involved the combination of these cases with those reported in the literature, estimating the mean relative risk and, for each gene, the heterogeneity of the results thus collected. No relation was found between class I (A and B) HLA antigens and asbestosis. The authors suggest extension of this study to class II (DR) and III (components of complement) antigens and to seek possible links between combinations of antigens and the development of asbestosis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Asbestose
/
Antígenos HLA
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Fr
Revista:
Poumon Coeur
Ano de publicação:
1983
Tipo de documento:
Article