Complete development of Cryptosporidium in cell culture.
Science
; 224(4649): 603-5, 1984 May 11.
Article
em En
| MEDLINE
| ID: mdl-6710159
ABSTRACT
Protozoan parasites of the genus Cryptosporidium cause a short-term, flu-like, gastrointestinal illness in immunocompetent persons and severe, persistent, life-threatening diarrhea in immunodeficient individuals. No effective therapy is available for the treatment of cryptosporidiosis in the immunodeficient host. Complete development (from sporozoite to sporulated oocyst) of a human isolate of Cryptosporidium was achieved in cultured human fetal lung cells and primary chicken kidney and porcine kidney cells. The growth of this newly recognized zoonotic agent in cell culture now provides a means of studying its behavior, development, and metabolism, and a mechanism for evaluation of potentially useful therapeutic agents.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Coccídios
Tipo de estudo:
Etiology_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Science
Ano de publicação:
1984
Tipo de documento:
Article