A comparison of the onset of action and therapeutic efficacy of amoxapine and amitriptyline.
J Clin Psychiatry
; 39(7): 633-7, 1978 Jul.
Article
em En
| MEDLINE
| ID: mdl-681295
ABSTRACT
A total of 61 moderately to severely depressed outpatients were treated for four weeks with either amoxapine (a dibenzoxapine tricyclic) or amitriptyline. This double blind study showed that amoxapine was as effective as amitriptyline and had an earlier onset of action. Maximum doses used were 300 mg of amoxapine and 150 mg of amitriptyline. Side effects were similar for the two drugs, except for impotence or loss of libido in eight male amoxapine, as against three amitriptyline patients. Laboratory, EKG, and vital signs findings showed no pathological trends.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtorno Bipolar
/
Depressão
/
Dibenzoxazepinas
/
Amitriptilina
/
Amoxapina
Tipo de estudo:
Clinical_trials
Limite:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Clin Psychiatry
Ano de publicação:
1978
Tipo de documento:
Article