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Ornithine oxoacid aminotransferase found in AH 130 ascites hepatoma cells.
Biochim Biophys Acta ; 714(2): 356-60, 1982 Feb 02.
Article em En | MEDLINE | ID: mdl-7055619
We found heterogenous ornithine oxoacid aminotransferase (L-ornithine: 2-oxo-acid aminotransferase, EC 2.6.1.1.3) in rat ascites hepatoma AH 130 cells. Compared with enzymes from normal rat tissues, this heterogenous enzyme showed larger Km values for 2-oxoglutarate, a different elution-profile upon affinity chromatography with 2-oxoglutarate, more anionic mobility upon polyacrylamide gell electrophoresis, and a clearly different salting-out property upon ammonium sulfate fractionation. Similar heterogeneity of this aminotransferase was found in human cancer cells.
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ornitina-Oxo-Ácido Transaminase / Transaminases / Neoplasias Hepáticas Experimentais Limite: Animals / Humans Idioma: En Revista: Biochim Biophys Acta Ano de publicação: 1982 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ornitina-Oxo-Ácido Transaminase / Transaminases / Neoplasias Hepáticas Experimentais Limite: Animals / Humans Idioma: En Revista: Biochim Biophys Acta Ano de publicação: 1982 Tipo de documento: Article