Ornithine oxoacid aminotransferase found in AH 130 ascites hepatoma cells.
Biochim Biophys Acta
; 714(2): 356-60, 1982 Feb 02.
Article
em En
| MEDLINE
| ID: mdl-7055619
We found heterogenous ornithine oxoacid aminotransferase (L-ornithine: 2-oxo-acid aminotransferase, EC 2.6.1.1.3) in rat ascites hepatoma AH 130 cells. Compared with enzymes from normal rat tissues, this heterogenous enzyme showed larger Km values for 2-oxoglutarate, a different elution-profile upon affinity chromatography with 2-oxoglutarate, more anionic mobility upon polyacrylamide gell electrophoresis, and a clearly different salting-out property upon ammonium sulfate fractionation. Similar heterogeneity of this aminotransferase was found in human cancer cells.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ornitina-Oxo-Ácido Transaminase
/
Transaminases
/
Neoplasias Hepáticas Experimentais
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Biochim Biophys Acta
Ano de publicação:
1982
Tipo de documento:
Article