[New data from a comparative study of cerebral blood volume and EEG during epileptic seizures in Papio papio (author's transl)]. / Donnees nouvelles apportees par l'etude correlative du volume sanguin cerebral et de l'EEG au cours de crises e'epilepsie chez le Papio papio.

ABSTRACT

A new approach to the cerebral and extracerebral circulation phenomenon, during generalized seizure discharges (GSD) in the baboon is described. It is based upon the measurement of comparative variations of the regional blood volume (RBV) a new technique. First results demonstrate the existence of an extracerebral vascular structure of the face which is quite sensitive to the ictal phenomenon and which we have named the 'nasal region'. On the whole, when bursts of spike/waves occur the mean arterial blood pressure (MBP) and cerebral blood volume (CBV) increase moderately whereas the nasal blood volume (NBV) decreases. During the generalized seizure discharge, variations are much larger, increasing for MBP and CBV and decreasing for NBV. CBV variations do not passively follow those of MBP.