Abnormality of the X chromosome in human 46,XY female siblings with dysgenetic ovaries.
Science
; 207(4432): 768-9, 1980 Feb 15.
Article
em En
| MEDLINE
| ID: mdl-7352285
ABSTRACT
An abnormal extra band was found on the short arm of the X chromosome in a 46,XY female and in her 46,XY female fetal sibling. Despite presence of the intact Y chromosome, there was no evidence of testicular differentiation in either subject. Production of H-Y antigen was suppressed in both subjects. The data suggest that development of the mammalian testis requires a normal function of the X chromosome.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Aberrações dos Cromossomos Sexuais
/
Cromossomos Sexuais
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Cromossomo X
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Disgenesia Gonadal
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Disgenesia Gonadal 46 XY
Limite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Science
Ano de publicação:
1980
Tipo de documento:
Article