Construction of human Y-chromosomal haplotypes using a new polymorphic A to G transition.
Hum Mol Genet
; 3(12): 2159-61, 1994 Dec.
Article
em En
| MEDLINE
| ID: mdl-7881413
ABSTRACT
We report the discovery of a polymorphic A to G transition found on the human Y chromosome by sequencing Y-specific sequence-tagged sites (STSs). It shows maximal linkage disequilibrium with a previously described Alu insertional polymorphism. We analyze further an apparently African Y chromosome which seems to have entered a Mexican Mayan population several generations ago. Using the newly discovered transition and the Y-specific polymorphic Alu insertion, we discuss how the chromosome's haplotype information might be used to answer questions of human origins and migrations.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Polimorfismo Genético
/
Cromossomo Y
/
Haplótipos
/
Mutação Puntual
Limite:
Animals
/
Humans
/
Male
Idioma:
En
Revista:
Hum Mol Genet
Assunto da revista:
BIOLOGIA MOLECULAR
/
GENETICA MEDICA
Ano de publicação:
1994
Tipo de documento:
Article