Post-radiation gliomas.
Tumori
; 80(3): 220-3, 1994 Jun 30.
Article
em En
| MEDLINE
| ID: mdl-8053080
ABSTRACT
AIMS AND BACKGROUND:
Radiotherapy is important in the treatment of neoplasm of the central nervous system, but various side effects, particularly neoplastic, have been described. Recently, post-radiation gliomas have been reported.METHODS:
The authors review 88 cases of cerebral glioma following radiotherapy in patients operated for neoplasms of the nervous system, including 6 personal cases of post-radiation gliomas treated in the Neurosurgical Division of the Department of Neurological Sciences, "La Sapienza" University, Rome. The criteria used to define this unusual pathologic association are discussed.RESULTS:
There was a male predominance. Post-radiation gliomas were particularly malignant, the average dose was 33 Gy, and average free latency was 9.6 years. The first disease was most frequently acute lymphatic leukemia.CONCLUSIONS:
Post-radiation gliomas have particular features but do not present a histologic or clinical behavior different from analogous spontaneous gliomas. The fact that 88 cases have been reported in recent years suggests that a thorough biological, clinical studies be carried out on this association.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Radioterapia
/
Neoplasias Encefálicas
/
Glioma
/
Neoplasias Induzidas por Radiação
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Tumori
Ano de publicação:
1994
Tipo de documento:
Article
País de afiliação:
Itália