Isolation of antirhinoviral sesquiterpenes from ginger (Zingiber officinale).
J Nat Prod
; 57(5): 658-62, 1994 May.
Article
em En
| MEDLINE
| ID: mdl-8064299
ABSTRACT
The dried rhizomes of Indonesian ginger, Zingiber officinale, were investigated for antirhinoviral activity in the plaque reduction test. Fractionation by solvent extraction, solvent partition, and repeated chromatography guided by bioassay, allowed the isolation of several sesquiterpenes with antirhinoviral activity. The most active of these was beta-sesquiphellandrene [2] with an IC50 of 0.44 microM vs. rhinovirus IB in vitro.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Antivirais
/
Plantas Medicinais
/
Rhinovirus
/
Sesquiterpenos
Limite:
Humans
Idioma:
En
Revista:
J Nat Prod
Ano de publicação:
1994
Tipo de documento:
Article
País de afiliação:
Reino Unido