Documentation of complete resolution of gestational choriocarcinoma in the oophorectomized patient.
Gynecol Oncol
; 51(2): 261-5, 1993 Nov.
Article
em En
| MEDLINE
| ID: mdl-8276305
ABSTRACT
A 39-year-old woman with choriocarcinoma metastatic to the lungs and parametrium underwent total abdominal hysterectomy/bilateral salpingo-oophorectomy and follow-up chemotherapy with regression of the hCG assay, plateauing at 9 mIU/ml. Spinal fluid hCG assay was negative. An LH assay was performed which was 135 mIU/ml (2nd IRP-HMG). A quantitative hCG assay was performed on two sources of purified LH at varying concentrations to determine the contribution of LH cross-reactivity. When corrected for the LH contribution, the quantitative hCG was zero. Chemotherapy was discontinued. At 12-months follow-up the patient has remained in complete chemical remission and has an excellent performance status. Whenever a patient is oophorectomized, LH cross-reactivity should be ruled out as a cause for persistent low titers of hCG.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Uterinas
/
Coriocarcinoma
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Gynecol Oncol
Ano de publicação:
1993
Tipo de documento:
Article