Germ-line p53 mutation is uncommon in patients with triple primary cancers.
Cancer Lett
; 73(1): 51-7, 1993 Sep 15.
Article
em En
| MEDLINE
| ID: mdl-8402598
ABSTRACT
We examined five patients with multiple primary cancers who had a history of three different types of primary cancers for germ-line p53 mutations. The germ-line p53 mutation was detected in a patient who conformed to the Li-Fraumeni syndrome, but not in the other four patients. The diagnosis of these four patients did not fall in the category of Li-Fraumeni syndrome. This result indicates that germ-line p53 mutations are uncommon even in patients with triple primary cancers.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Genes p53
/
Neoplasias Primárias Múltiplas
Limite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Cancer Lett
Ano de publicação:
1993
Tipo de documento:
Article
País de afiliação:
Japão