Radiographic and immunohistochemical analysis of leukocyte adhesion deficiency in Holstein heifers.
Can J Vet Res
; 59(4): 316-8, 1995 Oct.
Article
em En
| MEDLINE
| ID: mdl-8548695
ABSTRACT
Radiographic and immunohistochemical analyses were performed in two Holstein heifers with leukocyte adhesion deficiency (BLAD). Severe bone resorption, osteolysis and severe progressive periodontitis in submandibula due to dysfunction of leukocytes in heifers affected with BLAD were demonstrated by radiographic examination. Immunohistochemical analysis of lymph nodes using anti-CD18 monoclonal antibody demonstrated that CD18-positive cells were not found on those from a heifer affected with BLAD, whereas CD18-positive cells were clearly present in lymph nodes from a clinically normal heifer. These characteristic findings support the importance of adherence-dependent leukocyte functions in host defense.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças dos Bovinos
/
Síndrome da Aderência Leucocítica Deficitária
/
Antígenos CD18
/
Linfonodos
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
Idioma:
En
Revista:
Can J Vet Res
Assunto da revista:
MEDICINA VETERINARIA
Ano de publicação:
1995
Tipo de documento:
Article
País de afiliação:
Japão