Prostaglandin production by rheumatoid synovial cells: stimulation by a factor from human mononuclear Cells.
J Exp Med
; 145(5): 1399-1404, 1977 May 01.
Article
em En
| MEDLINE
| ID: mdl-859001
ABSTRACT
Human peripheral blood mononuclear cells (lymphocyte-monocyte) in culture release a solube factor which can stimulate, up to 200-fold, production of prostaglandin E2 by isolated, adherent, rheumatoid synovial cells. Production of the factor by the mononuclear cells is enhanced by phytohemagglutinin. This factor is similar in apparent mol vt (10,000-20,000) to that which also stimulates collagenase production by the same cells.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Artrite Reumatoide
/
Prostaglandinas E
/
Membrana Sinovial
/
Linfócitos
Limite:
Humans
Idioma:
En
Revista:
J Exp Med
Ano de publicação:
1977
Tipo de documento:
Article