Failure to detect paramyxovirus RNA in the skin of connective tissue disease.
J Dermatol Sci
; 11(1): 70-5, 1996 Jan.
Article
em En
| MEDLINE
| ID: mdl-8867770
ABSTRACT
Etiology of connective tissue disease is unknown. The association of infectious agents has been suspected serologically, ultrastructurally and recently by means of molecular biological techniques. We extracted RNA from lesions of 25 discoid lupus erythematosus, 9 systemic LE, and 3 systemic sclerosis biopsies, and reverse transcription-polymerase chain reaction was performed for all paramyxoviruses known to infect human beings. None of the samples yielded positive signal for any of the viruses. The existence of paramyxovirus in the skin of connective tissue disease is very unlikely.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pele
/
RNA Viral
/
Respirovirus
/
Doenças do Tecido Conjuntivo
Limite:
Humans
Idioma:
En
Revista:
J Dermatol Sci
Assunto da revista:
DERMATOLOGIA
Ano de publicação:
1996
Tipo de documento:
Article
País de afiliação:
Estados Unidos