Changes in the concentration of cortisol in amniotic fluid after intra-amniotic prostaglandin for midtrimester abortion.
Br J Obstet Gynaecol
; 84(8): 608-12, 1977 Aug.
Article
em En
| MEDLINE
| ID: mdl-889750
ABSTRACT
PIP: The effects of intraamniotic prostaglandin E2 (PGE2) and PGF2alpha on the concentrations of cortisol in amniotic fluid and in maternal peripheral plasma of patients undergoing abortion between weeks 16-23 have been examined. There was a significant (P0.01) increase in cortisol concentration in amniotic fluid 4 hours after PGE2, but not after PGF2alpha. The concentration of cortisol in maternal peripheral plasma increased in both groups with the progression of abortion, but levels were not significantly correlated with those in amniotic fluid. These results suggest that by midpregnancy, fetal cortisol production can be stimulated by PGE2 but the mechanism of this action remains to be elucidated.
Palavras-chave
Abortifacient Agents; Abortion, Drug Induced; Abortion, Induced; Abortion, Therapeutic; Age Factors; Amniocentesis--analysis; Biology; Endocrine System; Evaluation; Examinations And Diagnoses; Family Planning; Fertility Control, Postconception; Genetic Technics; Laboratory Examinations And Diagnoses; Physiology; Pregnancy; Pregnancy, Second Trimester; Prostaglandins--administraction and dosage; Reproduction
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hidrocortisona
/
Prostaglandinas
/
Aborto Induzido
/
Líquido Amniótico
Limite:
Adult
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Br J Obstet Gynaecol
Ano de publicação:
1977
Tipo de documento:
Article