Localization of a gene: the nucleolar organizer.
Biomedicine
; 30(6): 282-7, 1979 Dec.
Article
em En
| MEDLINE
| ID: mdl-93494
ABSTRACT
Nucleolus differentiates around the nucleolus organizer regions of the chromosomes or NORs. In the interphasic nucleoli the fibrillar centers are now considered as the NORs. The purpose of this editorial is to review the experimental data which allowed such identification. Our current concepts regarding this point result from three lines of evidence 1) specific localization during nucleologenesis, 2) in situ hybridization with labeled ribosomal RNA or DNA, and 3) specific staining with silver.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Mapeamento Cromossômico
/
Região Organizadora do Nucléolo
Idioma:
En
Revista:
Biomedicine
Ano de publicação:
1979
Tipo de documento:
Article