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[Several parameters of the state of the nervous, immune and endocrine systems in newborn rats exposed to irradiation during the preimplantation period of embryogenesis]. / Nekotorye pokazateli sostoianiia nervnoi, immunnoi i éndokrinnoi sistem u novorozhdennykh krys, podvergshikhsia oblucheniiu v doimplantasionnyi period émbriogeneza.
Filiushkin, I V; Ignatov, A N; Leshchenko, M V; Makashina, O M; Kashirin, V S; Stetsenko, A V; Gruden', M A; Shumova, E A; Bel'chenko, A N.
Afiliação
  • Filiushkin IV; State Research Centre of Russia Federation, Institute of Biophysics, Moscow.
Radiats Biol Radioecol ; 38(1): 15-26, 1998.
Article em Ru | MEDLINE | ID: mdl-9606401
Protracted prenatal irradiation of animals at the preimplantation stage of embryogenesis is shown to produce disturbances in the development of regulation systems, with their consequences persisting up to sexually mature period of postnatal life. Unknown before, these effects of preimplantation irradiation give the experimental confirmation to the main statement of the previously proposed theoretical concept of the "systemic teratogenesis": the ultimate effect of prenatal irradiation is a distortion of the structure of postnatal neuroimmunoendocrine regulation in the direction of overdevelopment of its endocrine component with the following coadaptive underdevelopment of the nervous and immune components.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anormalidades Induzidas por Radiação / Blastocisto / Sistema Endócrino / Sistema Imunitário / Sistema Nervoso Limite: Animals Idioma: Ru Revista: Radiats Biol Radioecol Assunto da revista: GENETICA / MEDICINA NUCLEAR Ano de publicação: 1998 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anormalidades Induzidas por Radiação / Blastocisto / Sistema Endócrino / Sistema Imunitário / Sistema Nervoso Limite: Animals Idioma: Ru Revista: Radiats Biol Radioecol Assunto da revista: GENETICA / MEDICINA NUCLEAR Ano de publicação: 1998 Tipo de documento: Article