Early postglomerular plasma concentrations of chloride, sodium, and inulin in the rat kidney.
Am J Physiol
; 231(3): 822-31, 1976 Sep.
Article
em En
| MEDLINE
| ID: mdl-970462
ABSTRACT
Sodium, chloride, and inulin concentrations were measured in plasma collected from the terminal portions of long efferent vessels at the subcapsular surface of the rat kidney. Sodium concentration equaled and the concentrations of chloride and inulin were less than those in peripheral plasma. During benzolamide infusion, chloride concentration equaled while inulin concentration remained less than in peripheral plasma. In free-flow micropuncture samples collected randomly during control conditions, chloride concentration rose rapidly in the early proximal tubule and then remained elevated and constant throughout the remainder of the proximal tubule accessible to micropuncture. These experiments indicate that normally tubular reabsorbate low in chloride and inulin is added to the blood traversing the early postglomerular vessels before reaching the kidney surface. Bases on the analyses of proximal tubular fluid, this type of reabsorbate appears available only from the early proximal tubular segment. We conclude that a close functional relationship exists between the first segment of the proximal tubule and the early postglomerular blood supply characteristic of the superficial cortical nephron.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sódio
/
Cloretos
/
Inulina
/
Túbulos Renais Proximais
Limite:
Animals
Idioma:
En
Revista:
Am J Physiol
Ano de publicação:
1976
Tipo de documento:
Article