Classical conditioning to hypoxia using odors as conditioned stimuli in rats.
Behav Neurosci
; 112(6): 1393-401, 1998 Dec.
Article
em En
| MEDLINE
| ID: mdl-9926821
ABSTRACT
The authors performed a differential conditioning experiment in 30 rats, using 2 odors as the conditioned stimuli (CS+ and CS-) and hypoxia (8% O2) as the unconditioned stimulus. Vanillin was the CS+ and rose the CS- in half of the rats, and vice versa in the other half. Fifteen paired CS+/hypoxia trials and 15 CS- only trials were performed in random order, followed by 3 CS+ only and 3 CS- only trials to test for conditioning. The increase in ventilation from prestimulus levels averaged 116 +/- 85% in response to CS+ versus 55 +/- 36% in response to CS-. This effect was supported by the significant Pre-Post Stimulus x CS Type interaction for this variable (p < .003). The data confirm the sensitivity of breathing to conditioning processes and also indirectly support the hypothesis that feedforward responses may complement feedback reflex pathways in respiratory homeostasis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oxigênio
/
Olfato
/
Condicionamento Clássico
Limite:
Animals
Idioma:
En
Revista:
Behav Neurosci
Ano de publicação:
1998
Tipo de documento:
Article
País de afiliação:
França