Effect of psychotropic drugs on taste responses in young and elderly persons.
Ann N Y Acad Sci
; 855: 732-7, 1998 Nov 30.
Article
em En
| MEDLINE
| ID: mdl-9929678
ABSTRACT
The taste of six psychotropic drugs (amitriptyline HCl, clomipramine HCl, desipramine HCl, imipramine HCl, doxepin HCl, and trifluoperazine HCl) can be detected at concentrations of 0.1 mM or less in both young and elderly individuals. At concentrations 4 times higher than the detection thresholds, these drugs have bitter as well as other unpleasant taste properties. Oral exposure to these drugs not only induces a taste from the drug itself but also alters taste perception of other compounds such as NaCl and sucrose. These results indicate that both hypogeusia and dysgeusia may be induced by psychotropic medications.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Psicotrópicos
/
Paladar
/
Envelhecimento
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Ann N Y Acad Sci
Ano de publicação:
1998
Tipo de documento:
Article
País de afiliação:
Estados Unidos