Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 32
Filtrar
Más filtros

Banco de datos
País/Región como asunto
Tipo del documento
País de afiliación
Intervalo de año de publicación
1.
J Craniofac Surg ; 31(6): e544-e546, 2020 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-32487835

RESUMEN

INTRODUCTION: Congenital unilateral lower lip palsy - also known as asymmetric crying facies - is isolated asymmetry of the lower lip unilaterally. It is characterized by isolated lower lip asymmetry during smiling and speech. Although etiology is unknown, depressor labii inferioris (DLI) weakness is hold responsible. AIM: Purpose of this study was to evaluate the effectiveness of contralateral depressor labii inferioris botulinum toxin injection on patients' concern levels and patient satisfaction. Ten units of botulinum toxin A injection was carried out to the healthy contralateral side. METHODOLOGY: Eleven patients were treated. Patients' pretreatment and posttreatment concern regarding asymmetry during speech and smiling was evaluated with a questionnaire. Patients' perception of treatment satisfaction was also evaluated with a questionnaire. RESULTS: Mean score related to concern about asymmetric appearance during smiling decreased from 1.6 ±â€Š0.8 to 0.5 ±â€Š0.5. Mean score related to concern about asymmetric appearance during speech decreased from 1.6 ±â€Š0.5 to 0.4 ±â€Š0.5. Eleven out of 11 patients reported improvement with speech whereas 10 out of 11 patients reported improvement with smiling. No weakness about oral competence was reported. CONCLUSION: Most congenital unilateral lower lip palsy patients are concerned regarding their asymmetric appearance while smiling or speaking. Chemodenervation of the contralateral DLI muscle reduces concern levels and has high patient satisfaction. Chemodenervation of the contralateral healthy DLI muscle is a valid, practical treatment option.


Asunto(s)
Parálisis Facial/tratamiento farmacológico , Labio/fisiopatología , Bloqueo Nervioso , Toxinas Botulínicas Tipo A/administración & dosificación , Toxinas Botulínicas Tipo A/uso terapéutico , Músculos Faciales/efectos de los fármacos , Músculos Faciales/fisiopatología , Parálisis Facial/congénito , Humanos , Satisfacción del Paciente , Sonrisa , Habla
2.
Facial Plast Surg ; 34(1): 59-65, 2018 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-29409105

RESUMEN

Patients with thick skin typically present with a redundant, baggy, lax skin envelope together with prominent nasolabial folds, jowls, and a heavy neck. Durable and natural-appearing rejuvenation is not possible unless the deformities are addressed adequately and harmoniously in these patients. Traditional superficial musculoaponeurotic system techniques do not include surgical release of the zygomatic cutaneous ligaments and repositioning of descendent malar fat pad, and may lead to an unbalanced, unnatural appearance and the lateral sweep phenomenon. Additional attempts to improve unopposed nasolabial folds such as fat grafting to malar region are more likely to result with a "stuffed" look, far from a natural and rejuvenated appearance, and must therefore be avoided. The facelift techniques including true release of the anchoring ligaments of the midface and allowing adequate repositioning of saggy tissues are ideal for these patients to obtain harmonious, natural result. Despite the extensive dissections, maximal release, and maximal lateral pull, additional maneuvers, e.g., platysmaplasty, subplatysmal fat removal, or partial resection of submandibular glands may be required for satisfying result in patients with heavy neck. In this article, the authors outline the relevant anatomy of the facial retaining ligaments and their implications to surgical management of patients with heavy skin are discussed.


Asunto(s)
Ligamentos/cirugía , Surco Nasolabial/cirugía , Cuello/cirugía , Ritidoplastia/métodos , Cicatrización de Heridas/fisiología , Cicatriz/prevención & control , Estética , Femenino , Humanos , Ligamentos/anatomía & histología , Masculino , Surco Nasolabial/anatomía & histología , Cuello/anatomía & histología , Rejuvenecimiento/fisiología , Medición de Riesgo , Envejecimiento de la Piel/fisiología , Técnicas de Sutura
3.
Aesthet Surg J ; 38(12): 1269-1279, 2018 Nov 12.
Artículo en Inglés | MEDLINE | ID: mdl-29509842

RESUMEN

BACKGROUND: Inadequate release of retaining ligaments during facelift surgery may lead to an unnatural appearance. However, most facelift surgeons are hesitant in transecting these ligaments to avoid possible injury to facial subbranches. OBJECTIVES: In the authors' surgical practice for modified composite flap rhytidectomy, the authors employed the finger-assisted malar elevation (FAME) technique in order to enable safe release of the zygomatic cutaneous ligaments through the prezygomatic space under direct vision. The aim was to evaluate the anatomical basis and safety measures of this technique through a cadaveric dissection study. METHODS: Modified composite-flap facelift with the FAME technique was carried out in 22 fresh cadaver hemi-faces. All facial nerve subbranches were dissected thoroughly to assess for any evidence of injury during facelift, and to evaluate the safety of the operation. The relations among the facial nerve, zygomatic cutaneous and masseteric ligaments, orbicularis oculi muscle, and malar fat pad were investigated. RESULTS: Finger dissection of the prezygomatic space allows safe release of the zygomatic cutaneous ligaments as well as adequate entry to a proper surgical plane above the zygomatici muscles under direct vision, while leaving the malar fat pad and overlying structures attached to the skin without the need of a transblepharoplasty approach. CONCLUSIONS: This study by the authors shows that a modified composite-flap facelift with FAME technique is a safe procedure that allows adequate and effective repositioning of an en-bloc composite flap that produces balanced and harmonious rejuvenation of the midface and lower face without the need of a separate midface lift.


Asunto(s)
Colgajo Miocutáneo , Rejuvenecimiento , Ritidoplastia/métodos , Adulto , Anciano , Cadáver , Mejilla , Músculos Faciales/trasplante , Femenino , Humanos , Ligamentos/cirugía , Masculino , Persona de Mediana Edad
4.
J Craniofac Surg ; 28(7): e707-e710, 2017 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-28863008

RESUMEN

INTRODUCTION: Neurologic involvement associated with Behçet disease (BD) is defined as a different entity: Neuro-Behçet disease (NBD). Behçet disease presents with olfactory dysfunction. It is not known whether this is the consequence of mucosal involvement or neurologic involvement. OBJECTIVE: The aim of this study was to investigate whether olfactory dysfunction was further aggravated as the result of neurologic involvement. METHODS: Sixteen patients diagnosed with NBD and 16 healthy control patients with similar demographic characteristics were recruited as the healthy control group. Expanded Disability Status Scale (EDSS) scoring was used for quantification of neurological disability. All diagnoses were confirmed and categorized with magnetic resonance imaging studies in all patients individually: parenchymal or nonparenchymal. A well-established test of orthonasal olfaction developed at the CCCRC was used. Correlation analysis was carried out. RESULTS: The mean CCCRC score of NBD patients was 4.60 out of 7, and this group was diagnosed to be moderately hyposmic, whereas the average score of the control group was 6.5; the difference was significant (P < 0.0001). CCCRC scores of NBD patients were significantly lower compared both healthy control patients and those of BD patients reported in the literature. Mean EDSS score of NBD patients was 1.75 ±â€Š1.0 out of 10 (0-no neurologic disability and 10-worst neurologic disability). Magnetic resonance imaging of NBD patients revealed 4 nonparenchymal and 12 parenchymal patients. Neuro-Behçet disease patients with parenchymal involvement presented with (worse) EDSS scores. Mean olfactory CCCRC score of this group was 4.38 whereas the average olfactory score of the vascular group was 5.25 out 7. Average EDSS score of vascular group was 0.75, much better compared to higher average neurologic disability score of 2.08 for the parenchymal group. Significant correlation existed between the duration of NBD and both olfactory and neurologic dysfunction scores. CONCLUSION: Neuro-Behçet disease present with aggravated olfactory dysfunction compared to BD. Neurologic involvement-especially parenchymal involvement-seems to deteriorate the olfactory dysfunction. Duration of disease is correlated with this severity of dysfunction.


Asunto(s)
Síndrome de Behçet , Trastornos del Olfato/etiología , Síndrome de Behçet/complicaciones , Síndrome de Behçet/epidemiología , Estudios de Casos y Controles , Humanos
5.
J Craniofac Surg ; 26(6): e515-7, 2015 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-26267582

RESUMEN

UNLABELLED: Facial paralysis is a significant functional and aesthetic handicap. Many techniques have been defined for facial reanimation. The aim of the study was to evaluate postoperative electromyographical (EMG) activity of temporalis muscle to assess the potential neural impairments related to the surgical procedure. METHODOLOGY: Four patients with facial paralysis were operated with the temporalis muscle tendon transfer technique. Simultaneous surface electromyographic (sEMG) activity at first postoperative year from the bilateral temporalis and masseter muscles was obtained at mandibular rest position and then during maximal clenching. RESULTS: Patients were followed for a minimum period of 18 months. Surface electromyographic evaluations during passive state revealed similar values for the operated and contralateral side. Measurements during active "clench-smiling" of the jaw revealed similar amplitudes for both muscles of the operated side in all cases except case #2. Case #2 revealed lower values for both measurements of temporalis and masseter muscles of the operated side compared with the contralateral side. Dissonant results of case #2 can be the consequence of impaired temporalis muscle activity because of the tension on the muscle as a consequence of overcorrection. CONCLUSION: Temporalis muscle transfer to the perioral region does not hinder contractility of the muscle as long as the facial deformity is not overcorrected.


Asunto(s)
Electromiografía/métodos , Parálisis Facial/cirugía , Procedimientos de Cirugía Plástica/métodos , Músculo Temporal/fisiología , Transferencia Tendinosa/métodos , Adulto , Femenino , Estudios de Seguimiento , Humanos , Masculino , Músculo Masetero/fisiología , Contracción Muscular/fisiología , Sonrisa/fisiología , Músculo Temporal/cirugía , Dimensión Vertical
6.
J Craniofac Surg ; 26(7): 2155-9, 2015 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-26468801

RESUMEN

AIM: Stiffness of the auricular cartilage is the main determining factor for the choice of operative technique of the prominent ear deformity. The aim of this study is to evaluate the stiffness of normal appearing ears objectively and quantitatively, compare the results with the operated prominent ear patients, and present prospective short-term dynamometric evaluation of the operated prominent ear patients. PATIENTS AND METHODS: A total of 190 volunteers without ear deformities were recruited and 9 age groups were formed: group (5-9), group (10-14), group (15-19), group (20-24), group (25-29), group (30-34), group (35-39), group (40-49), and group (50+). Total 28 ears (14 patients) with otoplasty were included in the study as group (operated 5-9) and group (operated 10-14). In addition, 3 patients with prominent ear deformity were prospectively followed for dynamometric changes that occur with otoplasty operation. The auriculocephalic angle (ACA) was measured once and auricle to scalp distance was measured at 4 different standardized levels. Ear stiffness was measured on each ear individually at 4 different points over the antihelix using digital computer-aided dynamometry. Each ear was compared in terms of ACA, distance, and dynamometric values. FINDINGS: Dynamometric values tend to increase with age, which increase and peak around 35 years of age and declines after 40 years of age. Measurements of the first 2 age groups were statistically different compared with the other groups. Postoperative dynamometric measurements (DNM) of group (operated 5-9) were similar with normative values of group (5-9) and postoperative satisfaction visual analogue scale (VAS) score was 92.8%. Postoperative DNM of group (operated 10-14) were higher compared with normative values of group (10-14) for each different measuring level and the postoperative satisfaction VAS score was 75.3. A total of 3 patients with prominent ears had lower dynamometric values preoperatively; these values approached closer to normative values of their age group postoperatively. CONCLUSIONS: Results show that auricular cartilage stiffens and malleability decreases with increased age. This stiffness peaks in the 35-39 age group and declines after 40 years of age. Dynamometric values increase, at all levels, suggesting increased cartilage stiffness is related to age. In the scope of these results, cartilage sparing techniques are more suitable for 5 to 14 years of age and cartilage-cutting techniques are more suitable for older patients.


Asunto(s)
Pabellón Auricular/fisiología , Cartílago Auricular/anomalías , Oído Externo/anomalías , Procedimientos de Cirugía Plástica/métodos , Adolescente , Adulto , Factores de Edad , Fenómenos Biomecánicos , Cefalometría/métodos , Niño , Preescolar , Pabellón Auricular/anatomía & histología , Cartílago Auricular/fisiopatología , Cartílago Auricular/cirugía , Oído Externo/fisiopatología , Oído Externo/cirugía , Elasticidad , Estética , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Satisfacción del Paciente , Estudios Prospectivos , Estudios Retrospectivos , Resultado del Tratamiento , Escala Visual Analógica , Adulto Joven
7.
Aesthetic Plast Surg ; 39(1): 25-35, 2015 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-25480746

RESUMEN

BACKGROUND: Because rhinoplastic surgery predominantly deals with the osseocartilaginous skeleton, droopy noses with thick skin remain a problem to be solved. In these noses, neglecting excess skin can impair long-lasting and complete correction of the nasal deformity. As these noses already require redundant dorsal skin resection, surgical manipulations can be executed entirely through the dorsal skin excision window instead of the transcolumellar approach. OBJECTIVE: The wide-open dorsal approach rhinoplasty (WoDAR) was developed to allow removal of excess dorsal skin and reconstruction of the nasal osseocartilaginous framework through the excised dorsal skin avoiding a transcolumellar incision. MATERIALS AND METHODS: Nine male patients with thick skin and significantly ptotic noses were operated with WoDAR. The cosmetic appearance of the noses was evaluated by the patients before and after the operation using a visual analog scale (VAS). The nasal obstruction symptom evaluation (NOSE) scale was evaluated individually preoperatively and postoperatively. The nasolabial angle (NLA) was measured preoperatively, at the third, twelfth, and twenty-fourth months postoperatively. Dorsal scars were evaluated by means of the Stony Brook's scar evaluation scale (SBSES). RESULTS: Patients (mean age: 51.4 ± 4.8 years) were followed for an average duration of 20.6 ± 8.4 months. Cosmetic evaluation revealed that the mean patient preoperative VAS score was 23.3 ± 25.6, whereas the postoperative VAS score was 92.6 ± 14.8. Preoperative and postoperative NOSE scores were 79.5 ± 16.5 and 11.5 ± 11.5, respectively. The mean preoperative NLA was 72.9 ± 2.9° and at the third and twelfth month postoperatively was 92 ± 6.5 and 91 ± 5.4. The NLA measurements of all four patients followed for 24 months revealed less than 2° derotation compared to third postoperative month. The mean SBSES score was 4.1 ± 0.8 out of 5. CONCLUSION: WoDAR allowed esthetically and functionally pleasing outcomes. This advantageous technique can be regarded as a surgical alternative for carefully selected aged patients with severely ptotic, thick-skinned noses who might otherwise end up with unsatisfying results both for surgeon and patients.


Asunto(s)
Rinoplastia/métodos , Procedimientos Quirúrgicos Dermatologicos , Humanos , Masculino , Persona de Mediana Edad , Nariz/anomalías , Nariz/cirugía
8.
Am J Otolaryngol ; 35(3): 305-8, 2014.
Artículo en Inglés | MEDLINE | ID: mdl-24667057

RESUMEN

AIM: This study introduces a new device to facilitate perforation size measurement during "butterfly" myringoplasty. The purpose of this study is to evaluate the use of 'otological compass' on short-term results of inlay cartilaginous 'butterfly' tympanoplasty technique in adult patients. STUDY DESIGN: Prospective, randomized, controlled, blinded. PATIENTS AND METHODS: This study included 25 patients who underwent inlay cartilage myringoplasty. All operations were performed under general anesthesia by the same surgeon with a microscope-assisted approach. The patients were divided randomly and consecutively into two groups: Group 1 (n=12) had perforation dimensions and shape measured using the Otologic Compass (OC) and the control group (n=13) had perforation measured by means of a Fisch elevator. The duration of surgery, number of trials for correct placement of the cartilage graft, results and complications of the surgery were evaluated and compared. RESULTS: The mean follow-up duration was 6 months. Groups were similar in terms of age and perforation diameters (p>0.05). Average number of cartilage shaping before satisfactory graft fitting was significantly fewer in the OC group: 1.1 ± 0.3 and 2.2 ± 0.6 trials for OC and control groups, respectively (p<0.001). Mean duration of preparation and satisfactory graft fitting was 9.6 ± 4.2 minutes in the OC group whereas it was 18.1 ± 5.2 minutes for the control group. Operative duration was significantly shorter in the OC group (p<0.001). At the end of the follow-up period, successful closure occurred 91.7% and 84.6% patients in the OC and control groups, respectively (p>0.05). The mean preoperative to postoperative three-tone air-bone gap improved 7.9 dB and 9.0 dB in OC and control groups, respectively (p>0.05). CONCLUSION: This study shows that OC presents as a useful tool that expedites and refines butterfly myringoplasty procedure. The number of cartilage shaping prior to satisfactory graft fitting revealed significantly better results: almost all surgeries in the OC group were complete after a single cartilage shaping attempt.


Asunto(s)
Miringoplastia/instrumentación , Miringoplastia/métodos , Perforación de la Membrana Timpánica/patología , Adulto , Humanos , Estudios Prospectivos
9.
Aesthetic Plast Surg ; 38(2): 322-8, 2014 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-24610112

RESUMEN

BACKGROUND: Reconstruction of the middle third of the nose is crucial and middle vault insufficiency is possible following dorsal reduction in a primary rhinoplasty unless additional surgical measures are taken. The aim of this study was to define a novel suturing technique autospreading spring flap for middle vault reconstruction by suturing only the medial aspect of both upper lateral cartilages with septal quadrangular cartilage in a unique mattress suture and to mimic the natural anatomical configuration of the upper lateral and septal cartilages. This technique is intended to create functionality with aesthetic dorsal lines. METHODS: Fifteen volunteers with a significant osseocartilaginous dorsal hump underwent open rhinoplasty. The middle vault was reestablished using the ASSF technique that appositions only the medial part of the upper lateral cartilages and suturing it to the dorsal septal cartilage. Appearance of the nose before and after the operation was evaluated by the patients using a visual analog scale. Acoustic rhinometry (AR) was carried out preoperatively and postoperatively to determine nasal valve patency. Preoperative and postoperative symptoms were evaluated and compared using the nasal obstruction symptom evaluation (NOSE) scale. RESULTS: Patients (mean age=32.2±6.3 years) were followed for a mean of 12.6 months. The preoperative NOSE score was 65.0±13 and the postoperative NOSE score was 7.7±10. Cosmetic evaluation revealed the mean patient preoperative VAS score was 32.5±20 and the postoperative VAS score was 88±9. AR revealed a mean minimal cross-sectional area of 1.56 cm2 that increased to 2.16 cm2 postoperatively. Intranasal total volume increased from 16.3 to 24.8 cm3 postoperatively. CONCLUSION: The newly defined autospreading spring flap suturing technique is a reliable method for reconstructing the nasal dorsum after humpectomy and for preventing middle vault and nasal valve collapse. The outcome was satisfactory, both aesthetically and functionally, but long-term follow-up is required. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .


Asunto(s)
Nariz/cirugía , Procedimientos de Cirugía Plástica/métodos , Rinoplastia/métodos , Colgajos Quirúrgicos/irrigación sanguínea , Técnicas de Sutura , Adulto , Estética , Femenino , Estudios de Seguimiento , Humanos , Cartílagos Nasales/cirugía , Tabique Nasal/cirugía , Nariz/anomalías , Cuidados Preoperatorios/métodos , Rinometría Acústica/métodos , Medición de Riesgo , Muestreo , Factores de Tiempo , Resultado del Tratamiento
10.
Artículo en Inglés | MEDLINE | ID: mdl-39058667

RESUMEN

In this short communication: (1) A transcutaneous electrical nerve stimulaton stimulator is a cost-effective solution for the predictable stimulation of mimicry and for precise decision-making. (2) Positioning a simple shatterproof mirror in front of an operated facial half enables the primary surgeon to simultaneously see and stimulate at the operative site and to scrutinize the mimicry for decision-making. (3) A misconception in the literature regarding colors used for tagging "branches for transection" and "branches for preservation" is clarified, and a third tag-color is suggested for times of ambiguity. (4) The principle of distal execution of the surgery and technical considerations are underlined for maximal transection and maximal preservation. The modified selective neurectomy surgery is the current golden standard of post facial paralysis synkinesis treatment, and developing a learning curve in this type of surgery is like walking a tightrope, where the surgeon must keep pushing the limits with precise decision-making and a small margin of error. It is important to be reminded that the first aim is primum non nocere, and the second aim is to improve the condition of patients as much as possible. The above-mentioned principles and solutions increase precision and safety, assisting surgeons to achieve better outcomes.

11.
Eur Arch Otorhinolaryngol ; 269(12): 2505-10, 2012 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-22350430

RESUMEN

A novel method for repair of septal perforations. Fifteen volunteers with symptomatic septal perforations were recruited. Open technique rhinoplasty approach was preferred: auricular conchal cartilage graft with intact perichondrium on both sides was harvested and shaped to fit the perforated site and attached to the septum with absorbable sutures. All margins of the graft were covered with nasal mucosa. The severity of patient symptoms was assessed at preoperation, 3 and 6 months postoperatively via visual analogue scale (VAS). Crust formation, whistling, nasal blockage, epistaxis and overall comfort were evaluated. Mucosal physiology was assessed by nasal mucociliary clearance time. The mean age of the patients was 47.3 years. Average perforation size was 1.86 ± 0.78 cm. 14/15 (93.3%) perforations were repaired, and only one patient required revision surgery. VAS scores improved significantly (p < 0.001). Mean mucociliary clearance time improved from 17.6 ± 3.83 to 10.3 ± 3.30 min and 9.3 ± 3.36 min at 3 and 6 months, respectively. This is a novel, simple and safe method for repairing the deficient mucosal area in septal perforations up to 25 mm in diameter.


Asunto(s)
Cartílago Auricular/trasplante , Mucosa Nasal/fisiología , Perforación del Tabique Nasal/cirugía , Regeneración , Rinoplastia/métodos , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Depuración Mucociliar , Resultado del Tratamiento , Cicatrización de Heridas
12.
J Craniofac Surg ; 23(4): 970-3, 2012 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-22777442

RESUMEN

OBJECTIVES: Smoking plays an important role in oral cancer development; however, the molecular carcinogenesis mechanism in oral mucosa is not well understood. The aim of this study was to examine and compare the levels of p65 nuclear factor κB (NF-κB), p38 mitogen-activated protein kinase (MAPK), and inducible nitric oxide synthase (iNOS) expressions between oral mucosa of nonsmoker and smoker volunteers. METHODS: Oral cheek mucosa was collected from 78 volunteers. Smokers were divided into 2 subgroups: light smokers (<40 pack years) and heavy smokers (≥ 40 pack years). Paraffinized tissue immunochemistry was carried out for p65 NF-κB, p38 MAPK, and iNOS expression with specific antibodies. Results were evaluated based on diffuseness and intensity of staining. RESULTS: Group 1 composed of 40 nonsmokers: 52.5% were female and 47.5% were male, with a mean age of 46.4 years. Group 2 composed of 38 smokers (20 light smokers, 18 heavy smokers): 39.5% were female and 60.5% were male, with a mean age of 48.9 years. Total immunohistochemical staining scores of smokers were significantly higher compared with those of nonsmokers in p65 NF-κB, p38 MAPK, and iNOS expression (P < 0.001). The highest p65 NF-κB, p38 MAPK, and iNOS expression levels were detected in the oral mucosa of heavy smokers. The expression of iNOS and p65 NF-κB in heavy smokers was significantly higher compared to that in light smokers (P < 0.01 and P < 0.05, respectively). Although p38 MAPK expressions were higher in heavy smokers compared with light smokers, the difference was not statistically significant (P > 0.05). CONCLUSIONS: Our results show for the first time the significant increase in the expression of p65 NF-κB and p38 MAPK in the oral mucosa of smokers. Levels of p65 NF-κB, p38 MAPK, and iNOS expression in the oral mucosa of smokers were related to the number of pack years.


Asunto(s)
Mucosa Bucal/metabolismo , FN-kappa B/metabolismo , Óxido Nítrico Sintasa de Tipo II/metabolismo , Fumar/metabolismo , Proteínas Quinasas p38 Activadas por Mitógenos/metabolismo , Análisis de Varianza , Biopsia , Distribución de Chi-Cuadrado , Femenino , Humanos , Inmunohistoquímica , Masculino , Persona de Mediana Edad
13.
Kulak Burun Bogaz Ihtis Derg ; 22(2): 77-80, 2012.
Artículo en Inglés | MEDLINE | ID: mdl-22548263

RESUMEN

OBJECTIVES: The aim of this study was to investigate whether UPSIT (The University of Pennsylvania Smell Identification Test) clinical olfactory function test is suitable to assess olfactory function in Turkish population. PATIENTS AND METHODS: Fifty healthy Turkish volunteers (21 males, 29 females; mean age 31.5±8.7 years; range 20 to 49 years) who underwent a detailed otorhinolaryngological examination were included in the study. Subjects with abnormal findings suggesting olfactory dysfunction were excluded from the study. UPSIT and Connecticut Chemosensory Clinical Research Center (CCCRC) tests were carried out for each individual separately. RESULTS: Mean CCCRC test score was 6.3±0.6 out of 7. Ten volunteers scored between 5-5.75 were considered mild hyposmia, while 40 volunteers scored between 6-7 were evaluated as normosmic. Volunteers correctly identified 21.4±4.7 odors out of 40 odors in UPSIT test. CONCLUSION: We concluded that UPSIT test is insufficient for the evaluation of olfactory function in Turkish population. Our results suggest that UPSIT test contains odors which are unfamiliar to Turkish population. Therefore, it is essential to either modify odors of UPSIT test or establish normative data suitable to Turkish population for evaluating the scores to avoid false olfactory function assessment.


Asunto(s)
Trastornos del Olfato/diagnóstico , Percepción Olfatoria/fisiología , Olfato , Adulto , Pruebas Diagnósticas de Rutina/normas , Femenino , Humanos , Masculino , Persona de Mediana Edad , Trastornos del Olfato/epidemiología , Valores de Referencia , Turquía/epidemiología , Adulto Joven
16.
Facial Plast Surg Aesthet Med ; 22(4): 286-293, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32392429

RESUMEN

Importance: Using asymmetric dorsal preservation (ADP) (pushdown technique for deviated side and letdown technique to the contralateral nondeviated side) is an alternative surgical method to correct osseocartilaginous deviation in crooked nose deformity. Objective: Aim of this study was to evaluate whether ADP rhinoplasty is a good method to address I-shaped crookedness in comparison with conventional midvault deconstructing/reconstructing rhinoplasty. Design, Setting, and Participants: This study was conducted between June 2017 and August 2019. Twenty-two consecutive patients' I-shaped crookedness was addressed with either ADP (n = 10) or conventional midvault techniques (n = 12). Patients were followed up at least for 6 months. Main Outcomes and Measures: Pre- and postoperative frontal photographs and digital screen protractor was utilized for measurement of crookedness in a single-blinded manner. Surgical success were calculated and compared. Results: In ADP group, mean angle of deviation was 10.2 ± 3.7° and 0.5 ± 1.0° pre- and postoperatively, respectively. In control group, mean angle of deviation was 9.5 ± 1.8° and 0.3 ± 0.9° pre- and postoperatively, respectively. Change in angle was statistically significant for both groups. Postoperative calculated mean success rate was 96.3 ± 7.9% and 97.5 ± 8.5% for dorsal preservation and control group, respectively. Eight out of 10 patients in dorsal preservation group and 11 out of 12 patients in the control group achieved the ideal angle of 0°, hence had 100% postoperative surgical success. Conclusions and Relevance: Utilization of dorsal preservation principles for correction of I-shaped crookedness presents as a promising and practical surgical alternative approach that should be in every rhinoplasty surgeon's armamentarium.


Asunto(s)
Nariz/anomalías , Rinoplastia/métodos , Adolescente , Adulto , Femenino , Estudios de Seguimiento , Humanos , Masculino , Nariz/cirugía , Método Simple Ciego , Resultado del Tratamiento , Adulto Joven
17.
Turk Arch Otorhinolaryngol ; 58(4): 249-253, 2020 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-33554200

RESUMEN

OBJECTIVE: Distal masseter-to-facial neurorrhaphy is an option to improve smile excursion in facial paralysis patients in the early period without truncating the facial nerve truncus and by ensuring the continuity of the facial nerve. This study aimed to study the effect of distal masseter-to-facial neurorrhaphy on smile excursion. METHODS: Charts of eight patients were retrospectively examined. Screenshots showing the best possible smiles were taken from preoperative videos. Screenshots were taken from postoperative videos showing the best combination of a natural smile on the healthy side and a smile with clenched teeth on the paralytic side. Emotrics and Photoshop software were used for computing vertical, horizontal, and overall excursion from facial landmarks. Scaled measurements of improvement in lip excursion and lip angle was evaluated. Symmetry was evaluated by accepting the healthy side as 100 percent, and the paralytic side was calculated as a percentage of the healthy side. RESULTS: Five patients had total facial paralysis and three had facial paresis. Mean postoperative follow-up period was 15.0±10.2 months. The average interval between facial denervation and nerve repair was 14.0±4.1 months (range, 11-23). All neurorrhaphies were coapted end-to-end to either the zygomatic or the buccal branch without an interposition graft. Mean postoperative initial movement occurred at 95.5±20.5 days (range, 72-138). Paralytic side to healthy side horizontal excursion changed from preoperative 72.5±17.4% to postoperative 93.4±6.9%. Vertical excursion changed from preoperative 38.4±24.6% to postoperative 89.3±11.8%. Overall excursion changed from preoperative 68.4±19.6% to postoperative 92.9±10.4%. Paralytic side to healthy side mean lip angle changed from 64.7% preoperative to 95.2% postoperatively. All changes were statistically significant (p<0.05). CONCLUSION: Facial paralysis patients with an asymmetric smile benefit from distal masseter-to-facial nerve transfer and it improves smile excursion dramatically. This effect was especially prominent in the vertical component of the smiling vector.

18.
JAMA Facial Plast Surg ; 20(2): 136-140, 2018 Mar 01.
Artículo en Inglés | MEDLINE | ID: mdl-28975239

RESUMEN

IMPORTANCE: Postoperative pain at the donor site is a common morbidity following autologous costal cartilage grafting. OBJECTIVE: To evaluate postoperative pain at the donor site after the use of a muscle-sparing costal cartilage harvesting technique compared with a muscle-cutting technique using electrocautery. DESIGN, SETTING, AND PARTICIPANTS: Designed as a controlled trial without randomization, this prospective, comparative cohort study was conducted between January 1, 2016, and March 31, 2017. Participants included 20 patients who underwent rhinoplasty for various cosmetic and functional complaints from January 1, 2016, to February 28, 2017. Of the 20 patients, 1 was excluded owing to an infection that developed on postoperative day (POD) 7. Patients were grouped by the rib harvesting technique used that was either a muscle-sparing technique (n = 11) or a muscle-cutting technique (n = 8). Skin incisions for both groups were carried out with a blade. Transection of muscle fascia and muscle fibers was performed with monopolar electrocautery in the muscle-cutting technique group. Blunt dissection with a hemostat was performed in the muscle-sparing technique group. All other surgical techniques were identical. MAIN OUTCOMES AND MEASURES: Postoperative pain was assessed with visual analog scale scores for resting pain and movement pain. Eight pain measurements were noted at the sixth postoperative hour and on PODs 1, 2, 3, 7, 15, 30, and 45. During the hospital stay, the postoperative need for analgesics was recorded daily as the number of analgesic infusion vials used. RESULTS: The 19 patients in the study included 11 women and 8 men whose mean age (SD) was 33.2 (10.3) years The mean (SD) visual pain analog scale scores for resting pain and movement pain were consistently higher in the muscle-cutting technique group than in the muscle-sparing technique group. This difference was statistically significant on PODs 2, 3, and 15 for resting pain and on PODs 2, 3, 7, 15, 30, and 45 for movement pain. The mean postoperative need for analgesic infusion vials during hospital stay was higher in the muscle-cutting technique group, and the difference was statistically significant on POD 2 (1.9 [0.6] vials vs 1.0 [0.9] vials; P = .02). CONCLUSIONS AND RELEVANCE: Both resting and movement pain at the donor site was significantly reduced in the muscle-sparing technique group during the postoperative period, findings that align with anecdotal reports in the literature. Routine use of the muscle-sparing technique in autologous costal cartilage harvesting is recommended to reduce postoperative pain. LEVEL OF EVIDENCE: 2.


Asunto(s)
Cartílago Costal/trasplante , Dolor Postoperatorio/prevención & control , Rinoplastia/métodos , Recolección de Tejidos y Órganos/métodos , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Dimensión del Dolor , Dolor Postoperatorio/diagnóstico , Dolor Postoperatorio/etiología , Estudios Prospectivos , Trasplante Autólogo , Resultado del Tratamiento
19.
Curr Opin Otolaryngol Head Neck Surg ; 24(4): 309-15, 2016 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-27159652

RESUMEN

PURPOSE OF REVIEW: To review recent studies on nasal osseocartilaginous anatomy, osteotomy techniques and contemporary methods of nasal bone reshaping carried out under direct vision. RECENT FINDINGS: Current cadaver studies on osseocartilaginous vault anatomy, osteotomy techniques provide valuable information that can reduce outcome variability and increase reliability of osteotomies. Nevertheless, osteotomes have limitations and contemporary approaches - namely, piezoelectric instrumentations, osteoectomy, and osteotomy carried out under direct vision - can provide valuable solutions to certain shortcomings. Contrary to widespread understanding, extended wide periosteal dissection is the common thread in newly introduced methods which claim enhanced control, reduced soft tissue trauma, and reproducible results. Comparative and cadaver studies show promising results regarding protection of underlying mucosa, reduced comminuted fractures, reduced postoperative ecchymosis, and edema. SUMMARY: Improvements in nasal bone reshaping are promising for better esthetic and functional outcomes. Nevertheless, these approaches need to be validated by randomized controlled trials and test of time before being incorporated in routine surgical practice.


Asunto(s)
Hueso Nasal/cirugía , Osteotomía/métodos , Rinoplastia/métodos , Humanos
20.
Kulak Burun Bogaz Ihtis Derg ; 26(3): 169-71, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-27107604

RESUMEN

Sarcoidosis is a multi-system disease which rarely involves the upper respiratory tract, leading to hoarseness, dysphagia, laryngeal paralysis, and upper airway obstruction. The Waldeyer's ring involvement in sarcoidosis is also very rare. In this article, we report a 32-year-old male case in whom a nasopharyngeal mass was detected based on the Waldeyer's ring involvement due to sarcoidosis.


Asunto(s)
Neoplasias Nasofaríngeas/patología , Sarcoidosis/patología , Humanos , Masculino
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA