[Duodenal villous atrophy, an unexpectedly common finding in giardia lamblia infestation]. / Atrofia villositaria duodenal, un hallazgo inesperadamente frecuente en infestación por giardia lamblia.

OBJECTIVE: To study the histological changes observed in Giardia positive biopsies obtained from the duodenum.: The number of intraepithelial lymphocytes (IEL), grade of villous atrophy, presence of lymph follicles and number of eosinophils in the lamina propria per HPF were assessed. METHODS: All giardia positive biopsies diagnosed during period 2005-2009 in 5 pathology units were reevaluated by a group of pathologists. RESULTS: Thirty cases were included. Atrophic villous architecture was seen in 61,2%, increase in number of intraepithelial lymphocytes in 63,3% The occurrence of lymphoid follicles in 43,3%. DISCUSSION: Villous atrophy was higher than reported by others authors, cases with atrophy showed greater frequency of increase in the number of intraepithelial lymphocytes than cases without atrophy. No cases with lymph follicle showed lack of plasmatic cells, the number of eosinophils was subtly increased.

Leishmaniasis cutánea verrugosa: expresión morfológica inusual / Verrucous cutaneous leishmaniasis: unusual morphological expression

La leishmaniasis es una zoonosis reemergente, que en su forma cutánea, presenta una gran diversidad clínica, por lo que se le llegó a denominar enfermedad de múltiples caras, y este polimorfismo clínico obliga a plantear múltiples diagnósticos diferenciales.Presentamos el caso de un paciente varón de 18 años de edad con un tiempo de enfermedad de seis meses, que presentaba múltiples placas de aspecto verrugoso en la cara interna de la rodilla derecha.

Leishmaniasis is a re-emerging zoonosis, that, in its cutaneousform, presents a wide range of clinical, so it came to be knew as disease of many faces, and this clinical polymorphism forces to raise multiple differential diagnosis. We present the case of a male patient 18 years of age with a time of six months disease,which featured multiple plates of warty appearance on inner sideof right knee region.

Atrofia villositaria duodenal, un hallazgo inesperadamente frecuente en infestación por Giardia lamblia / Duodenal villous atrophy, a finding unexpectedly frequent infestation by Giardia lamblia

Objetivo: Estudiar la presencia y frecuencia de los cambios histopatológicos tales como atrofia villositaria, linfocitosis intraepitelial, hiperplasia linfoide nodular y presencia de eosinófilos en biopsis duodenales informadas como Giardiasis. Metodología: Se recolectó todos los casos diagnosticados como giardiasis duodenal durante el período 2005 a 2009 en 5 diferentes servicios de anatomía patológica y fueron revisados por un grupo de patólogos. Resultados: Se incluyeron 30 casos. Se observó atrofia de las vellosidades en el 61,2%, incremento de linfocitos intraepiteliales en 63,3%, presencia de folículos linfoides en el 43,3% el promedio de eosinófilos en lámina propia por campo de alto poder fue aprox. 7. Discusión: Nuestro porcentaje de atrofia villositaria es mucho mayor que lo reportado por otros autores, los casos con atrofia presentaron mayor frecuencia de linfocitosis 83,3% que los casos sin atrofia. (30%). Este hallazgo coincide con la relación directa entre linfocitos intraepiteliales /atrofia de vellosidades descrita por varios autores. Ninguno de los casos con hiperplasia linfoide, presentó ausencia de células plasmáticas que nos hiciera sospechar histológicamente de algún tipo de inmunodepresión humoral. El número de eosinófilos encontrado fue levemente elevado.

Objective: To study the histological changes observed in Giardia positive biopsies obtained from the duodenum.: The number of intraepithelial lymphocytes (IEL), grade of villous atrophy, presence of lymph follicles and number of eosinophils in the lamina propria per HPF were assessed. Methods: All giardia positive biopsies diagnosed during period 2005-2009 in 5 pathology units were reevaluated by a group of pathologists. Results: Thirty cases were included. Atrophic villous architecture was seen in 61,2%, increase in number of intraepithelial lymphocytes in 63,3% The occurrence of lymphoid follicles in 43,3%. Discussion: Villous atrophy was higher than reported by others authors, cases with atrophy showed greater frequency of increase in the number of intraepithelial lymphocytes than cases without atrophy. No cases with lymph follicle showed lack of plasmatic cells, the number of eosinophils was subtly increased.