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1.
Int J Sports Med ; 45(6): 443-449, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38113921

RESUMEN

This study aimed to assess the seasonal evolution of field-based and laboratory-based performance indicators in cyclists. Thirteen Junior male road cyclists (age 17.4±0.5 years) were followed up during a season, which was divided in three phases: early season (involving mainly training sessions), mid-season (including the first competitions), and late season (including the major competitions of the season). During each phase, field-based power output data were registered for the assessment of maximum mean power values, and laboratory-based endurance (ramp test and simulated 8-minute time trial), muscle strength/power (squat, lunge, hip thrust) and body composition indicators (dual-energy X-ray absorptiometry) were also assessed. A progressive (p<0.01) increase in maximum mean power values (e.g., 3.8±0.3 and 4.5±0.4 watts/kg in early and late season, respectively, for 60-minute efforts) and on 8-minute time trial performance (i.e., 5.3±0.3 and 5.6±0.4 watts/kg, respectively) was observed through the season. Yet, more "traditional" endurance indicators (i.e., ventilatory threshold, respiratory compensation point, or maximum oxygen uptake) seemed to show a ceiling effect beyond the mid-season. In addition, neither peak power output, body composition, nor muscle strength indicators followed a similar pattern to the aforementioned field-based indicators. In summary, in Junior cyclists field-based indicators seem more sensitive to monitor endurance cyclists' changes in actual fitness and performance capacity than more "traditional" laboratory-based markers in Junior cyclists.


Asunto(s)
Rendimiento Atlético , Ciclismo , Fuerza Muscular , Consumo de Oxígeno , Resistencia Física , Estaciones del Año , Humanos , Ciclismo/fisiología , Masculino , Rendimiento Atlético/fisiología , Resistencia Física/fisiología , Adolescente , Fuerza Muscular/fisiología , Consumo de Oxígeno/fisiología , Composición Corporal , Absorciometría de Fotón , Prueba de Esfuerzo/métodos , Conducta Competitiva/fisiología , Factores de Tiempo
2.
Sensors (Basel) ; 24(6)2024 Mar 21.
Artículo en Inglés | MEDLINE | ID: mdl-38544265

RESUMEN

We aimed to determine the feasibility, test-retest reliability and long-term stability of a novel method for assessing the force (torque)-velocity (cadence) profile and maximal dynamic force (MDF) during leg-pedaling using a friction-loaded isoinertial cycle ergometer and a high-precision power-meter device. Fifty-two trained male cyclists completed a progressive loading test up to the one-repetition maximum (1RM) on a cycle ergometer. The MDF was defined as the force attained at the cycle performed with the 1RM-load. To examine the test-retest reliability and long-term stability of torque-cadence values, the progressive test was repeated after 72 h and also after 10 weeks of aerobic and strength training. The participants' MDF averaged 13.4 ± 1.3 N·kg-1, which was attained with an average pedal cadence of 21 ± 3 rpm. Participants' highest power output value was attained with a cadence of 110 ± 16 rpm (52 ± 5% MDF). The relationship between the MDF and cadence proved to be very strong (R2 = 0.978) and independent of the cyclists' MDF (p = 0.66). Cadence values derived from this relationship revealed a very high test-retest repeatability (mean SEM = 4 rpm, 3.3%) and long-term stability (SEM = 3 rpm, 2.3%); despite increases in the MDF following the 10-week period. Our findings support the validity, reliability and long-term stability of this method for the assessment of the torque-cadence profile and MDF in cyclists.


Asunto(s)
Ciclismo , Ergometría , Humanos , Masculino , Torque , Reproducibilidad de los Resultados , Pie , Prueba de Esfuerzo/métodos
3.
J Strength Cond Res ; 37(5): 1131-1134, 2023 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-36607237

RESUMEN

ABSTRACT: Muriel, X, Hernández-Belmonte, A, Mateo-March, M, Valenzuela, PL, Zabala, M, Barranco-Gil, D, Lucia, A, and Pallares, JG. Is the record power profile repeatable? A practical analysis and interpretation in professional cyclists. J Strength Cond Res 37(5): 1131-1134, 2023-This study assessed the repeatability of the Record Power Profile (RPP, i.e., the highest power output that a cyclist can attain for different effort durations under field-based conditions). We registered the RPP of 12 professional cyclists (age 32 ± 5 years) for efforts lasting between 30 seconds and 60 minutes during 3 periods of a season, each of 23-day duration: preparation (including training data only), specific (training and competition data), and competition (competition data only) periods. Repeatability was assessed using the highest 2 (RPP 2 ), 3 (RPP 3 ), and 5 (RPP 5 ) values of mean maximum power obtained by the cyclists for each effort duration in each of the 3 periods. Smaller standard errors of measurement ( SEM ) were found as the competitive period approached, especially for short-duration efforts (i.e., 30 seconds, 1 minute, and 5 minutes, where SEM ranged from 4.3 to 12.5%, 4.1-8.5%, and 2.6-7.0% in the preparation, specific, and competition periods, respectively). However, similar SEM values were found in the 3 periods for RPP 2 , RPP 3 , or RPP 5. In conclusion, the RPP appears as a repeatable parameter for monitoring field-based performance within the different phases of the season in professional cyclists.


Asunto(s)
Rendimiento Atlético , Humanos , Adulto , Ciclismo , Factores de Tiempo , Estaciones del Año
4.
Biol Sport ; 40(4): 1169-1176, 2023 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-37867760

RESUMEN

Different laboratory-based variables are individually associated with cycling performance, but scarce evidence exists on which of them, when all assessed in combination, could best explain cycling performance. The present study aimed to examine the combined association between laboratory-based endurance, strength/power and body composition indicators with time trial performance in high-level cyclists. Ninety-four male cyclists were recruited (age: 20 ± 3.5 years, maximum oxygen uptake [V̇O2max]: 77.7 ± 5.4 ml · kg-1 · min-1). Participants performed a maximal incremental cycling test for the assessment of endurance indicators (peak power output [PPO], V̇O2max, ventilatory threshold [VT] and respiratory compensation point [RCP]), and an incremental loading test to assess muscle strength and power-related outcomes (1-repetition maximum, mean maximal power) in the squat, lunge and hip-thrust exercises. Body composition was assessed by dual energy X-ray absorptiometry. On a separate visit, participants performed a simulated 8-minute time trial to assess cycling performance (determined as the mean power output attained). Strong-to-very-strong correlations were found between all endurance indicators and time trial performance (most r-values ranging between 0.68-0.92), whereas weaker correlations were found for strength/power (r-values < 0.5) or body composition (r-values < 0.7) indicators. Multivariate regression analyses revealed that VT, RCP and PPO explained together 92% of the variance in time trial performance (p < 0.001), with no significant contribution of the remaining variables. Although different endurance, strength/power and body composition individually correlate with simulated time trial performance in high-level cyclists, the former (and particularly VT, RCP and PPO) show the strongest association when all studied in combination. These findings underscore the importance of endurance capabilities (above strength/power or body composition) for maximizing time trial performance.

5.
Int J Sports Med ; 42(14): 1281-1286, 2021 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-34255327

RESUMEN

The present study aimed to assess the effects of an injury prevention program in CrossFit athletes. Thirty-two CrossFit athletes were randomized to either an intervention group (n=16), that performed mobility and stability exercises during the warm-up of all CrossFit sessions for a 10-week period or to a control group (n=16) that kept performing their usual warm-up. Incidence of injuries (primary outcome) as well as average training loads, fatigue and pain perception were registered during the study. The overall injury incidence rate was 0.04 per 1000 training hours, with no differences between groups (p>0.05). Similarly, no between-group differences were found for injury severity, nor for average training volume, intensity, training load, pain, or fatigue perception during the study (all p>0.05 with trivial-to-small effect sizes). In summary, a 10-week injury prevention program consisting of stability and mobility exercises provided no benefits on injury rates, fatigue and pain perception in recreational CrossFit athletes. Further research might corroborate the preliminary evidence reported here.


Asunto(s)
Traumatismos en Atletas/prevención & control , Ejercicio Físico , Ejercicio de Calentamiento , Atletas , Fatiga , Humanos , Proyectos Piloto , Equilibrio Postural
6.
Sensors (Basel) ; 21(7)2021 Mar 24.
Artículo en Inglés | MEDLINE | ID: mdl-33805150

RESUMEN

Cycling power meters enable monitoring external loads and performance changes. We aimed to determine the concurrent validity of the novel Favero Assioma Duo (FAD) pedal power meter compared with the crank-based SRM system (considered as gold standard). Thirty-three well-trained male cyclists were assessed at different power output (PO) levels (100-500 W and all-out 15-s sprints), pedaling cadences (75-100 rpm) and cycling positions (seating and standing) to compare the FAD device vs. SRM. No significant differences were found between devices for cadence nor for PO during all-out efforts (p > 0.05), although significant but small differences were found for efforts at lower PO values (p < 0.05 for 100-500 W, mean bias 3-8 W). A strong agreement was observed between both devices for mean cadence (ICC > 0.87) and PO values (ICC > 0.81) recorded in essentially all conditions and for peak cadence (ICC > 0.98) and peak PO (ICC > 0.99) during all-out efforts. The coefficient of variation for PO values was consistently lower than 3%. In conclusion, the FAD pedal-based power meter can be considered an overall valid system to record PO and cadence during cycling, although it might present a small bias compared with power meters placed on other locations such as SRM.

7.
Int J Sports Med ; 40(9): 592-596, 2019 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-31291652

RESUMEN

This study analyzed the relationship between CrossFit performance and power and strength variables measured in the full-squat exercise. Twenty male trained subjects (33±7 years) performed an incremental load full-squat test for assessment of the 1-repetition maximum (1RM) and the mean (Pmean) and peak (Ppeak) power. Performance in 5 different Workouts of the Day (WODs) was measured on different days, and overall CrossFit performance was determined as the sum of the scores obtained in these WODs. Athletes were then assigned to a high (HP) or low (LP) performance group based on the median score for overall performance. Correlation analysis between squat variables and performance was performed and between-group differences were assessed. Moderate to strong (r=0.47-0.69, p<0.05) positive correlations were found between squat variables and performance in the different WODs. Overall CrossFit performance was strongly and positively associated with absolute (r=0.62, p=0.01) and relative 1RM (r=0.65, p=0.07), and relative Pmean (r=0.56, p=0.02) and Ppeak (r=0.53, p=0.03). Large differences (effect sizes ranging 1.1-1.7, all p<0.05) were observed between HP and LP for absolute and relative 1RM, relative Pmean, and absolute and relative Ppeak. In summary, strength and power indexes measured in a squat test are positively associated with CrossFit performance.


Asunto(s)
Rendimiento Atlético/fisiología , Prueba de Esfuerzo , Fuerza Muscular , Músculo Esquelético/fisiología , Postura , Adulto , Humanos , Masculino , Contracción Muscular
8.
J Appl Physiol (1985) ; 136(2): 432-436, 2024 Feb 01.
Artículo en Inglés | MEDLINE | ID: mdl-38174376

RESUMEN

Cycling Grand Tours are arguably the epitome of strenuous endurance exercise, and they have been reported to represent the ceiling of sustained energy expenditure for humans. It remains unknown, however, if an average recreational athlete could endure such an event. Through the analysis of power output (PO), we compared data from the 2023 Tour de France (21 stages, total distance = 3,405 km, elevation gain = 51,815 m) in a recreational (male, age = 58 yr; height = 191 cm; body mass = 96.1 kg; estimated maximum oxygen uptake = 45.4 mL·kg-1·min-1) and a sex-matched professional (World-Tour) cyclist (28 yr; 180 cm; 67.0 kg; 80.5 mL·kg-1·min-1). The recreational and professional cyclist completed the event in 191 and 87 h, respectively (average PO of 1.50 and 3.45 W·kg-1), with the latter spending a greater proportion of time in high-intensity zones. The recreational cyclist showed an estimated total daily energy expenditure (TDEE) of 35.9 MJ [or 8,580 kcal, or ∼4.3× his daily basal metabolic rate (BMR)], whereas lower absolute values were estimated for the professional cyclist (29.7 MJ, 7,098 kcal, ∼3.8× his BMR). Despite such high TDEE values, both individuals lost minimal body mass during the event (0-2 kg). The present report therefore suggests that, partly due to differences in exercise intensity and duration, not only professional cyclists but also recreational athletes can reach currently known ceilings of TDEE for humans.NEW & NOTEWORTHY This case report indicates that a recreationally trained 58-year-old man can reach similar or even higher values of energy expenditure (∼4 times their basal metabolic rate) than professional cyclists, who are likely near the ceiling of sustained energy expenditure for humans. This was possible owing to a total longer exercise time coupled with a lower absolute and relative intensity in the recreational athlete.


Asunto(s)
Consumo de Oxígeno , Resistencia Física , Humanos , Masculino , Persona de Mediana Edad , Oxígeno , Ciclismo , Francia
9.
Int J Sports Physiol Perform ; 19(10): 1006-1011, 2024 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-39069285

RESUMEN

PURPOSE: To assess the effect of 2 work-matched efforts of different intensities on subsequent performance in well-trained cyclists. METHODS: The present study followed a randomized controlled crossover design. Twelve competitive junior cyclists volunteered to participate (age, 17 [1] y; maximum oxygen uptake, 71.0 [4.7] mL·kg-1·min-1). The power-duration relationship was assessed through 2-minute, 5-minute, and 12-minute field tests under fresh conditions (control). On subsequent days and following a randomized order, participants repeated the aforementioned tests after 2 training sessions matched for mechanical work (∼15 kJ/kg) of different intensities (ie, a moderate-intensity continuous-training [60%-70% of critical power; CP] session or a session including high-intensity intervals [3-min repetition bouts at 110%-120% of the CP interspersed by 3-min rest periods]). RESULTS: A significantly lower power output was found in the 2-minute test after the high-intensity training session compared not only with the control condition (-8%, P < .001) but also with the moderate-intensity continuous-training session (-7%, P = .003), with no significant differences between the latter conditions. No significant differences between conditions were found for the remaining tests. As a consequence, the high-intensity training session resulted in significantly lower W' values compared to both the control condition (-27%, P = .001) and the moderate-intensity continuous-training session (-26%, P = .012), with no differences between the 2 latter conditions and with no differences for CP. CONCLUSION: A session including high-intensity intermittent efforts induces a greater fatigue, particularly in short-duration efforts and W', than a work-matched continuous-training session of moderate intensity.


Asunto(s)
Rendimiento Atlético , Ciclismo , Estudios Cruzados , Consumo de Oxígeno , Humanos , Ciclismo/fisiología , Rendimiento Atlético/fisiología , Consumo de Oxígeno/fisiología , Adolescente , Masculino , Entrenamiento de Intervalos de Alta Intensidad , Acondicionamiento Físico Humano/métodos , Prueba de Esfuerzo , Factores de Tiempo
10.
Int J Sports Physiol Perform ; 19(6): 545-549, 2024 Jun 01.
Artículo en Inglés | MEDLINE | ID: mdl-38531349

RESUMEN

BACKGROUND: Durability (ie, the ability to attenuate the decline in performance after accumulated work) has been identified as a performance determinant in elite cyclists. The aim of the present study was to compare durability in elite cyclists of various performance levels, particularly after high-intensity work, referred to as "high-intensity durability." METHODS: Forty-nine (N = 49) male road cyclists were categorized as either under 23 years of age (U23) (N = 11), Pro Team (N = 13), or World Tour (N = 24). The participants' critical power (CP) was assessed during the preseason. Thereafter, the participants' maximum mean power (MMP) values were determined for efforts of different durations (from 5 s to 30 min) after different levels of accumulated work above CP (from 0 to 7.5 kJ·kg-1). RESULTS: U23 cyclists showed a significant reduction of all relative MMP values for durations ≥1 minute after ≥5 kJ·kg-1 above CP compared with the "fresh" state (0 kJ·kg-1), whereas in Pro Team and World Tour cyclists, a significant reduction was not observed until 7.5 kJ·kg-1 above CP. In the "fresh" state, both Pro Team and particularly World Tour cyclists attained higher MMP values for efforts ≥10 minutes than U23 riders. However, more differences emerged with greater previous work levels, and indeed after 7.5 kJ·kg-1 above CP World Tour cyclists attained higher MMP values than both U23 and Pro Team cyclists for most efforts (≥30 s). CONCLUSION: Pro Team and particularly World Tour cyclists tolerate greater levels of accumulated work at high intensity, which might support the importance of high-intensity durability for performance.


Asunto(s)
Rendimiento Atlético , Ciclismo , Humanos , Ciclismo/fisiología , Masculino , Rendimiento Atlético/fisiología , Adulto Joven , Factores de Tiempo
11.
J Sci Med Sport ; 27(6): 430-434, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38604818

RESUMEN

OBJECTIVES: Although the ability to attenuate power output (PO) declines after accumulated work (i.e., 'durability') is increasingly recognized as a major determinant of cycling performance, the potential role of the intensity of the previous work is unclear. We assessed the effect of work-matched levels of accumulated work at different intensities on performance in male professional cyclists. DESIGN: Observational field-based study. METHODS: PO data was registered in 17 cyclists during a competition season, and the critical power (CP) was repeatedly determined every 4 weeks from training sessions and competitions. Participants' maximum mean power (MMP) for different durations (5 s, 5 min, 10 min, and 20 min) and the CP were determined under 'fresh' conditions (0 kJ·kg-1) and after varying levels of accumulated work (2.5, 5.0 and 7.5 kJ·kg-1) at intensities below and above the CP. RESULTS: A significant decline was found for all MMP values following all levels of accumulated work above the CP (-4.0 %, -1.7 %, -1.8 %, and -3.2 % for 30s, 5 min, 10 min and 20 min-MMP, respectively; all p < 0.001), versus no change after any level of accumulated work below the CP (all p > 0.05). Similar results were observed for the CP, which decreased after all levels of accumulated work above (-2.2 %, -6.1 %, and -16.2 %, after 2.5, 5.0 and 7.5 kJ·kg-1, p < 0.001) but not below this indicator (p > 0.05). CONCLUSIONS: In male professional cyclists, accumulated work above the CP impairs performance compared with work-matched, albeit less intense efforts. This raises concerns on the use of mechanical work per se as a single fatigue/stress indicator in these athletes.


Asunto(s)
Rendimiento Atlético , Ciclismo , Humanos , Masculino , Ciclismo/fisiología , Rendimiento Atlético/fisiología , Adulto , Adulto Joven , Esfuerzo Físico/fisiología
12.
J Int Soc Sports Nutr ; 21(1): 2340574, 2024 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-38606895

RESUMEN

BACKGROUND: Growing evidence supports the ergogenic effects of creatine supplementation on muscle power/strength, but its effects on endurance performance remain unclear. We assessed the effects of high-dose short-term creatine supplementation in professional cyclists during a training camp. METHODS: The study followed a double-blind, randomized parallel design. Twenty-three professional U23 cyclists (19 ± 1 years, maximum oxygen uptake: 73.0 ± 4.6 mL/kg/min) participated in a 6-day training camp. Participants were randomized to consume daily either a recovery drink (containing carbohydrates and protein) with a 20-g creatine supplement (creatine group, n = 11) or just the recovery drink (placebo group, n = 12). Training loads and dietary intake were monitored, and indicators of fatigue/recovery (Hooper index, countermovement jump height), body composition, and performance (10-second sprint, 3-, 6-, and 12-minute time trials, respectively, as well as critical power and W') were assessed as study outcomes. RESULTS: The training camp resulted in a significant (p < 0.001) increase of training loads (+50% for total training time and + 61% for training stress score, compared with the preceding month) that in turn induced an increase in fatigue indicators (significant time effect [p < 0.001] for delayed-onset muscle soreness, fatigue, and total Hooper index) and a decrease in performance (significant time effect [p = 0.020] for critical power, which decreased by -3.8%). However, no significant group-by-time interaction effect was found for any of the study outcomes (all p > 0.05). CONCLUSIONS: High-dose short-term creatine supplementation seems to exert no consistent beneficial effects on recovery, body composition or performance indicators during a strenuous training period in professional cyclists.


Asunto(s)
Rendimiento Atlético , Humanos , Rendimiento Atlético/fisiología , Creatina , Suplementos Dietéticos , Método Doble Ciego , Fatiga , Músculo Esquelético , Oxígeno/metabolismo , Consumo de Oxígeno , Adolescente , Adulto Joven
13.
J Sci Med Sport ; 27(9): 660-663, 2024 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-38839539

RESUMEN

We quantified and compared the mechanical force demands relative to the maximum dynamic force (MDF) of 11 cyclists when pedaling at different intensities (ventilatory threshold, maximum lactate steady state, respiratory compensation point, and maximal aerobic power), cadences (free, 40, 60 and 80 rpm), and all-out resisted sprints. Relative force demands (expressed as %MDF) progressively increased with higher intensities (p < 0.001) and lower cadences (p < 0.001). Notwithstanding, relative force demands were low (<54 % MDF) for all conditions, even during the so-called 'torque training'. These results might be useful when programming on-bike resistance training to improve torque production capacity.


Asunto(s)
Ciclismo , Humanos , Ciclismo/fisiología , Masculino , Adulto , Ácido Láctico/sangre , Torque , Adulto Joven , Consumo de Oxígeno/fisiología , Entrenamiento de Fuerza/métodos , Fenómenos Biomecánicos
14.
Med Sci Sports Exerc ; 2024 Sep 03.
Artículo en Inglés | MEDLINE | ID: mdl-39231694

RESUMEN

PURPOSE: This study compared the effects of off- and on-bike resistance training (RT) on endurance cycling performance as well as muscle strength, power and structure. METHODS: Well-trained male cyclists were randomly assigned to incorporate two sessions/week of off- (full squats, n = 12) or on-bike (all-out efforts performed against very high resistances and thus at very low cadences, n = 12) RT during 10 weeks, with all RT-related variables [number of sessions, sets, and repetitions, duration of recovery periods, and relative loads (70% of one-repetition maximum)] matched between the two groups. A third, control group (n = 13) did not receive any RT stimulus but all groups completed a cycling training regime of the same volume and intensity. Outcomes included maximum oxygen uptake (V̇O2max), off-bike muscle strength (full squat) and on-bike ('pedaling') muscle strength and peak power capacity (Wingate test), dual-energy X-ray absorptiometry-determined body composition (muscle/fat mass), and muscle structure (cross-sectional area, pennation angle). RESULTS: No significant within/between-group effect was found for V̇O2max. Both the off- (mean Δ = 2.6-5.8%) and on-bike (4.5-7.3%) RT groups increased squat and pedaling-specific strength parameters after the intervention compared to the control group (-5.8--3.9%) (p < 0.05) with no significant differences between them. The two RT groups also increased Wingate performance (4.1% and 4.3%, respectively, vs. -4.9% in the control group, p ≤ 0.018), with similar results for muscle cross-sectional area (2.5% and 2.2%, vs. -2.3% in the control group, p ≤ 0.008). No significant within/between-group effect was found for body composition. ConclusionsThe new proposed on-bike RT could be an effective alternative to conventional off-bike RT training for improving overall and pedaling-specific muscle strength, power, and muscle mass.

15.
Clin Nutr ; 43(3): 692-700, 2024 03.
Artículo en Inglés | MEDLINE | ID: mdl-38320460

RESUMEN

BACKGROUND & AIMS: Ketone supplementation is gaining popularity. Yet, its effects on exercise performance when muscle glycogen cannot be used remain to be determined. McArdle disease can provide insight into this question, as these patients are unable to obtain energy from muscle glycogen, presenting a severely impaired physical capacity. We therefore aimed to assess the effects of acute ketone supplementation in the absence of muscle glycogen utilization (McArdle disease). METHODS: In a randomized cross-over design, patients with an inherited block in muscle glycogen breakdown (i.e., McArdle disease, n = 8) and healthy controls (n = 7) underwent a submaximal (constant-load) test that was followed by a maximal ramp test, after the ingestion of a placebo or an exogenous ketone ester supplement (30 g of D-beta hydroxybutyrate/D 1,3 butanediol monoester). Patients were also assessed after carbohydrate (75 g) ingestion, which is currently considered best clinical practice in McArdle disease. RESULTS: Ketone supplementation induced ketosis in all participants (blood [ketones] = 3.7 ± 0.9 mM) and modified some gas-exchange responses (notably increasing respiratory exchange ratio, especially in patients). Patients showed an impaired exercise capacity (-65 % peak power output (PPO) compared to controls, p < 0.001) and ketone supplementation resulted in a further impairment (-11.6 % vs. placebo, p = 0.001), with no effects in controls (p = 0.268). In patients, carbohydrate supplementation resulted in a higher PPO compared to ketones (+21.5 %, p = 0.001) and a similar response was observed vs. placebo (+12.6 %, p = 0.057). CONCLUSIONS: In individuals who cannot utilize muscle glycogen but have a preserved ability to oxidize blood-borne glucose and fat (McArdle disease), acute ketone supplementation impairs exercise capacity, whereas carbohydrate ingestion exerts the opposite, beneficial effect.


Asunto(s)
Enfermedad del Almacenamiento de Glucógeno Tipo V , Glucógeno , Humanos , Glucemia , Suplementos Dietéticos , Cetonas , Músculos , Estudios Cruzados
16.
Med Sci Sports Exerc ; 2024 Aug 20.
Artículo en Inglés | MEDLINE | ID: mdl-39160758

RESUMEN

INTRODUCTION: Whether cardiac impairment can be fully discarded in McArdle disease-the paradigm of 'exercise intolerance', caused by inherited deficiency of the skeletal muscle-specific glycogen phosphorylase isoform ('myophosphorylase')-remains to be determined. METHODS: Eight patients with McArdle disease and seven age/sex-matched controls performed a 15-minute moderate, constant-load cycle-ergometer exercise bout followed by a maximal ramp test. Electrocardiographic and two-dimensional transthoracic (for cardiac dimension's assessment) and speckle tracking [for left-ventricle global longitudinal (GLS) assessments] echocardiographic evaluations were performed at baseline. Electrocardiographic and GLS assessments were also performed during constant-load exercise and immediately upon maximal exertion. Four human heart biopsies were obtained in individuals without McArdle disease, and in-depth histological/molecular analyses were performed in McArdle and wild-type mouse hearts. RESULTS: Exercise intolerance was confirmed in patients ('second wind' during constant-load exercise, -55% peak power output vs controls). As opposed to controls, patients showed a decrease in GLS during constant-load exercise, especially upon second wind occurrence, but with no other between-group difference in cardiac structure/function. Human cardiac biopsies showed that all three glycogen phosphorylase-myophosphorylase, but also liver and especially brain-isoforms are expressed in the normal adult heart, thereby theoretically compensating for eventual myophosphorylase deficiency. No overall histological (including glycogen depots), cytoskeleton, metabolic or mitochondrial (morphology/network/distribution) differences were found between McArdle and wild-type mouse hearts, except for lower levels of pyruvate kinase M2 and translocase of outer membrane 20 kDa subunit in the former. CONCLUSIONS: This study provides preliminary evidence that cardiac structure and function seem to be preserved in patients with McArdle disease. However, the role for an impaired cardiac contractility associated with the second wind phenomenon should be further explored.

17.
Int J Sports Physiol Perform ; 18(11): 1275-1282, 2023 Nov 01.
Artículo en Inglés | MEDLINE | ID: mdl-37611911

RESUMEN

PURPOSE: Laboratory-based indicators are commonly used for performance assessment in young cyclists. However, evidence supporting the use of these indicators mostly comes from cross-sectional research, and their validity as predictors of potential future performance remains unclear. We aimed to assess the role of laboratory variables for predicting transition from U23 (under 23 y) to professional category in young cyclists. METHODS: Sixty-five U23 male road cyclists (19.6 [1.5] y) were studied. Endurance (maximal graded test and simulated 8-min time trial [TT]), muscle strength/power (squat, lunge, and hip thrust), and body composition (assessed with dual-energy X-ray absorptiometry) indicators were determined. Participants were subsequently followed and categorized attending to whether they had transitioned ("Pro") or not ("Non-Pro") to the professional category during the study period. RESULTS: The median follow-up period was 3 years. Pro cyclists (n = 16) showed significantly higher values than Non-Pro riders (n = 49) for ventilatory thresholds, peak power output, peak oxygen uptake, and TT performance (all P < .05, effect size > 0.69) and lower levels of fat mass and bone mineral content/density (P < .05, effect size > 0.63). However, no significant differences were found for muscle strength/power indicators (P > .05, effect size < 49). The most accurate individual predictor was TT performance (overall predictive value = 76% for a cutoff value of 5.6 W·kg-1). However, some variables that did not reach statistical significance in univariate analyses contributed significantly to a multivariate model (R2 = .79, overall predictive value = 94%). CONCLUSIONS: Although different "classic" laboratory-based endurance indicators can predict the potential of reaching the professional category in U23 cyclists, a practical indicator such as 8-minute TT performance showed the highest prediction accuracy.


Asunto(s)
Composición Corporal , Fuerza Muscular , Humanos , Masculino , Estudios Transversales , Densidad Ósea , Absorciometría de Fotón , Ciclismo/fisiología , Consumo de Oxígeno
18.
Int J Sports Physiol Perform ; 18(1): 99-103, 2023 Jan 01.
Artículo en Inglés | MEDLINE | ID: mdl-36521188

RESUMEN

PURPOSE: To assess durability in professional cyclists, as well as potential associated indicators. METHODS: Twelve male professional cyclists participated in the study (age: 26 [5] y, VO2max: 83.0 [3.6] mL·kg-1·min-1). They performed a 20-minute time trial (TT) on 2 different sessions separated by a 48-hour period: (1) with no previous fatigue (TTFresh) and (2) immediately after a long submaximal ride (approximately 4 h, 40 kJ/kg) (TTFatigue). We then assessed the decay (in percentage) in mean power output (PO) from TTFresh to TTFatigue and its association with different laboratory-based endurance indicators (ventilatory threshold, peak PO, and VO2max) determined through a previous maximal incremental cycling test, as well as with training loads during the 4 weeks preceding the TTs. RESULTS: While no differences were noted in the average heart rate (177 [7] vs 176 [6] beats·min-1, P = .118), there was a significant decay in PO between TTFresh and TTFatigue (386 [29] W vs 375 [28] W [-2.9%], respectively; P = .007), albeit with signs of interindividual variability (range = -8.5% to 1.1%; coefficient of variation = 105%). No significant associations were found between the PO decay and any of the analyzed indicators (all P > .05). CONCLUSIONS: Performance is significantly impaired after a certain amount of work completed (approximately 40 kJ·kg-1) in professional cyclists, and the magnitude of this impairment seems to be not related to "traditional" laboratory-based endurance indicators or to markers of training load. These findings might support the need for specifically assessing durability in cyclists and confirming potential determinants of this parameter.


Asunto(s)
Consumo de Oxígeno , Resistencia Física , Humanos , Masculino , Adulto , Ciclismo , Fatiga
19.
J Int Soc Sports Nutr ; 20(1): 2166366, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-36686220

RESUMEN

Background: The effects of pre-sleep protein supplementation on endurance athletes remain unclear, particularly whether its potential benefits are due to the timing of protein intake or solely to an increased total protein intake. We assessed the effects of pre-sleep protein supplementation in professional cyclists during a training camp accounting for the influence of protein timing. Methods: Twenty-four professional U23 cyclists (19 ± 1 years, peak oxygen uptake: 79.8 ± 4.9 ml/kg/min) participated in a six-day training camp. Participants were randomized to consume a protein supplement (40 g of casein) before sleep (n = 8) or in the afternoon (n = 8), or an isoenergetic placebo (40 g of carbohydrates) before sleep (n = 8). Indicators of fatigue/recovery (Hooper index, Recovery-Stress Questionnaire for Athletes, countermovement jump), body composition, and performance (1-, 5-, and 20-minute time trials, as well as the estimated critical power) were assessed as study outcomes. Results: The training camp resulted in a significant (p < 0.001) increase in training loads (e.g. training stress score of 659 ± 122 per week during the preceding month versus 1207 ± 122 during the training camp), which induced an increase in fatigue indicators (e.g. time effect for Hooper index p < 0.001) and a decrease in performance (e.g. time effect for critical power p = 0.002). Protein intake was very high in all the participants (>2.5 g/kg on average), with significantly higher levels found in the two protein supplement groups compared to the placebo group (p < 0.001). No significant between-group differences were found for any of the analyzed outcomes (all p > 0.05). Conclusions: Protein supplementation, whether administered before sleep or earlier in the day, exerts no beneficial effects during a short-term strenuous training period in professional cyclists, who naturally consume a high-protein diet.


Asunto(s)
Rendimiento Atlético , Humanos , Suplementos Dietéticos , Carbohidratos , Sueño , Fatiga , Ciclismo
20.
Int J Sports Physiol Perform ; 18(10): 1141-1144, 2023 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-37385604

RESUMEN

PURPOSE: The record power profile (RPP) has gained popularity as a method of monitoring endurance cycling performance. However, the expected variation of cyclists' performance between seasons remains unknown. We aimed to assess the between-seasons variability of peak performance (assessed through the RPP) in male professional cyclists. METHODS: The study followed a longitudinal observational design. Sixty-one male professional cyclists (age 26 [5] y) with power output data from both training sessions and competitions were analyzed for a median of 4 consecutive seasons (range 2-12). The highest mean maximum power values attained for different durations (from 10 s to 30 min), as well as the resulting critical power, were determined for each season. Within-cyclist variability between seasons was assessed, and the upper threshold of expected changes (ie, twice the normal coefficient of variation) was determined. RESULTS: All mean maximum power values showed an overall high agreement and low variability between seasons (intraclass correlation coefficient [ICC] = .76-.88 and coefficient of variation [CV] = 3.2%-5.9%), with the lowest variability observed for long efforts (>1 min). Critical power showed an ICC and CV of .79 (95% CI, .70-.85) and 3.3% (95% CI, 3.0%-3.7%), respectively. Upper thresholds of expected variation were <12% for short efforts (≤1 min) and <8% for long efforts. CONCLUSIONS: "Real-world" peak performance assessed through the RPP shows a low variability between seasons in male professional cyclists-especially for long efforts-with expected variation being around 6% and 3% for short (≤1 min) and long efforts, respectively, and with changes >12% and >8%, respectively, being infrequent for these effort durations.


Asunto(s)
Ciclismo , Estado Nutricional , Humanos , Masculino , Adulto , Estaciones del Año
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