Detalles de la búsqueda
1.
Phase I study of the anti-endothelin B receptor antibody-drug conjugate DEDN6526A in patients with metastatic or unresectable cutaneous, mucosal, or uveal melanoma.
Invest New Drugs
; 38(3): 844-854, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-31385109
2.
A phase I, randomized, observer-blinded, single and multiple ascending-dose study to investigate the safety, pharmacokinetics, and immunogenicity of BITS7201A, a bispecific antibody targeting IL-13 and IL-17, in healthy volunteers.
BMC Pulm Med
; 19(1): 5, 2019 Jan 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30616547
3.
Peripheral neuropathy with microtubule inhibitor containing antibody drug conjugates: Challenges and perspectives in translatability from nonclinical toxicology studies to the clinic.
Regul Toxicol Pharmacol
; 82: 1-13, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-27773754
4.
Randomized Phase II Study of the Safety and Efficacy of Semorinemab in Participants With Mild-to-Moderate Alzheimer Disease: Lauriet.
Neurology
; 101(14): e1391-e1401, 2023 10 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-37643887
5.
Safety and Efficacy of Semorinemab in Individuals With Prodromal to Mild Alzheimer Disease: A Randomized Clinical Trial.
JAMA Neurol
; 79(8): 758-767, 2022 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35696185
6.
A Phase 1 study of GDC-0134, a dual leucine zipper kinase inhibitor, in ALS.
Ann Clin Transl Neurol
; 9(1): 50-66, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35014217
7.
Phase 1 Study of the Anti-HtrA1 Antibody-binding Fragment FHTR2163 in Geographic Atrophy Secondary to Age-related Macular Degeneration.
Am J Ophthalmol
; 232: 49-57, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34214452
8.
Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer's disease.
Sci Transl Med
; 13(593)2021 05 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33980574
9.
A Phase I Study of DLYE5953A, an Anti-LY6E Antibody Covalently Linked to Monomethyl Auristatin E, in Patients with Refractory Solid Tumors.
Clin Cancer Res
; 26(21): 5588-5597, 2020 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32694157
10.
Phase I Study of DSTP3086S, an Antibody-Drug Conjugate Targeting Six-Transmembrane Epithelial Antigen of Prostate 1, in Metastatic Castration-Resistant Prostate Cancer.
J Clin Oncol
; 37(36): 3518-3527, 2019 12 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-31689155
11.
Isolated hypoxic hepatic perfusion with retrograde outflow in patients with irresectable liver metastases; a new simplified technique in isolated hepatic perfusion.
Ann Surg Oncol
; 15(5): 1367-74, 2008 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-18239976
12.
ABBY: A phase 2 randomized trial of crenezumab in mild to moderate Alzheimer disease.
Neurology
; 90(21): e1889-e1897, 2018 05 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-29695589
13.
Amyloid positron emission tomography and cerebrospinal fluid results from a crenezumab anti-amyloid-beta antibody double-blind, placebo-controlled, randomized phase II study in mild-to-moderate Alzheimer's disease (BLAZE).
Alzheimers Res Ther
; 10(1): 96, 2018 09 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-30231896
14.
Synergistic antitumor response of interleukin 2 with melphalan in isolated limb perfusion in soft tissue sarcoma-bearing rats.
Cancer Res
; 65(10): 4300-8, 2005 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15899822
15.
Phase I Study of DMOT4039A, an Antibody-Drug Conjugate Targeting Mesothelin, in Patients with Unresectable Pancreatic or Platinum-Resistant Ovarian Cancer.
Mol Cancer Ther
; 15(3): 439-47, 2016 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-26823490
16.
Histamine combined with melphalan in isolated limb perfusion for the treatment of locally advanced soft tissue sarcomas: preclinical studies in rats.
Acta Cir Bras
; 20(4): 275-9, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-16186945
17.
Isolated limb perfusion: distinct tourniquet and tumor necrosis factor effects on the early hemodynamic response.
Arch Surg
; 138(1): 17-25, 2003 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-12511144
18.
V-Y advancement flap for the reconstruction of partial and full thickness defects of the upper lip.
Scand J Plast Reconstr Surg Hand Surg
; 36(1): 28-33, 2002.
Artículo
en Inglés
| MEDLINE | ID: mdl-11925826
19.
TNF-based isolated limb perfusion: a decade of experience with antivascular therapy in the management of locally advanced extremity soft tissue sarcomas.
Cancer Treat Res
; 120: 65-79, 2004.
Artículo
en Inglés
| MEDLINE | ID: mdl-15217218
20.
Synergistic antitumor effects of histamine plus melphalan in isolated hepatic perfusion for liver metastases.
Ann Surg Oncol
; 14(2): 795-801, 2007 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-17096052