Overt Scientific Bias and Clandestine Acts by Trusted Scientists: The Flawed Application of the Linear No-threshold Model.

ABSTRACT: The Health Physics Society (HPS) released a video documentary on the history of the linear no-threshold (LNT) model in April 2022. It exposed many scientific and ethical failings of many leaders, influential scientists, and organizations that have resulted in the current system of radiological protection. Since then, the society received many comments; most were supportive, while a few criticized the video documentary as delivering an anti-LNT message. Shortly thereafter, many emails discovered via an independent Freedom of Information Act request revealed multiple layers of coordination between prominent people in the field of radiation protection to coopt the leadership within the HPS and suppress information they perceived or assumed to be contrary to a pro-LNT message. Many of these emails were published by JunkScience.com, an independent organization that exposes faulty scientific data and analyses used to advance special interests and hidden agendas. This Forum article is intended to document in the peer-reviewed literature the JunkScience.com findings of clandestine acts by trusted scientists within the radiation protection community. The emails exposed strong personal biases, actions taken by leaders within the National Commission on Radiation Protection and Measurements (NCRP) to "save the Society" from its "downward spiral," and actions taken by NCRP and HPS members serving on a National Academies of Sciences committee to suppress scientific information relevant to the debate about health effects in low-dose environments. These anti-science actions harm our entire profession and the trust that Congress bestows on our scientific organizations expecting to receive objective recommendations based on sound science. It is important that these events are recorded in the scientific literature from a historical perspective. The radiation protection community will be judged not by what is revealed in this article but by what actions are taken from here.

The History of the Linear No-Threshold Model and Recommendations for a Path Forward.

ABSTRACT: The intent of this paper and the accompanying video series is to inform the scientific community about the historical foundations that underpin the linear no-threshold (LNT) model's use for cancer risk assessment. There is a clear distinction here: this effort is about the history of how LNT came to be the regulatory paradigm and model for cancer risk assessment that it is today and not a discussion of the pros and cons of the LNT model. The overarching goal of this effort is to reframe the conversation around low-dose response models in light of this history and to determine how this history influences the scientific understanding of low-dose radiation responses. The timing of this series is intentional, as the International Commission on Radiological Protection (ICRP) has embarked on a mission to review the entire system of radiation protection. This effort necessarily requires rigorous scientific debate that must be based in fact. The history of the LNT model is paramount to this discussion, and it warrants consideration. Unfortunately, rather than engendering respectful debate, the topic of cancer risks associated with low dose radiation exposures has forged two disparate and sometimes contentious camps: (1) low doses, no matter how low, present some form of health risk and (2) an alternative model better represents the actual risks. The video series, conceived by John Cardarelli II, current President of the Health Physics Society (HPS), features Edward Calabrese, professor of toxicology in the School of Public Health and Health Sciences at the University of Massachusetts at Amherst, being interviewed by HPS Past-President Barbara Hamrick, CHP, JD, with support from Daniel Sowers, the Chair of the HPS Public Information Committee, and HPS Executive Director Brett Burk. Emily Caffrey, the Chief Editor of our Ask-the-Experts website (https://hps.org/publicinformation/ate/), was invited to watch the completed series as an independent peer reviewer. Further, an email address, factcheck@hps.org, was created to allow for peer-review by the scientific community to facilitate ongoing discussion and allow for corrections to the record as necessary. It is the sincere hope of this team that this work inspires new discussions about the system of radiological protection. We encourage everyone in this field to watch all 22 episodes to be informed about the underpinnings of current regulatory policy in the US.

Public health and environmental response to the first case of naturally acquired inhalational anthrax in the United States in 30 years: infection of a new york city resident who worked with dried animal hides.

In Pennsylvania on February 16, 2006, a New York City resident collapsed with rigors and was hospitalized. On February 21, the Centers for Disease Control and Prevention and the New York City Department of Health and Mental Hygiene were notified that Bacillus anthracis had been identified in the patient's blood. Although the patient's history of working with dried animal hides to make African drums indicated the likelihood of a natural exposure to aerosolized anthrax spores, bioterrorism had to be ruled out first. Ultimately, this case proved to be the first case of naturally occurring inhalational anthrax in 30 years. This article describes the epidemiologic and environmental investigation to identify other cases and persons at risk and to determine the source of exposure and scope of contamination. Because stricter regulation of the importation of animal hides from areas where anthrax is enzootic is difficult, public healthcare officials should consider the possibility of future naturally occurring anthrax cases caused by contaminated hides. Federal protocols are needed to assist in the local response, which should be tempered by our growing understanding of the epidemiology of naturally acquired anthrax. These protocols should include recommended methods for reliable and efficient environmental sample collection and laboratory testing, and environmental risk assessments and remediation.

Recovery, Resilience and Reality: Going Beyond NCRP Report No. 175.

Published in December 2014, National Council on Radiation Protection and Measurements Report No. 175, Decision Making for Late-Phase Recovery from Major Nuclear or Radiological Incidents, emphasizes the importance of local, state, and national plans addressing late-phase issues and decision-making processes concurrently with emergency response requirements. The report includes eight recommendations ranging from a broad call for a national strategy promoting community resilience as a preferred approach for preparing to recover from nuclear or radiological incidents to more specific calls for research and strategies for cleanup and waste management. This paper highlights how additional guidance may improve the nation's readiness to recover from a low-probability but high-concern incident.

It Is Time to Move Beyond the Linear No-Threshold Theory for Low-Dose Radiation Protection.

The US Environmental Protection Agency (USEPA) is the primary federal agency responsible for promulgating regulations and policies to protect people and the environment from ionizing radiation. Currently, the USEPA uses the linear no-threshold (LNT) model to estimate cancer risks and determine cleanup levels in radiologically contaminated environments. The LNT model implies that there is no safe dose of ionizing radiation; however, adverse effects from low dose, low-dose rate (LDDR) exposures are not detectable. This article (1) provides the scientific basis for discontinuing use of the LNT model in LDDR radiation environments, (2) shows that there is no scientific consensus for using the LNT model, (3) identifies USEPA reliance on outdated scientific information, and (4) identifies regulatory reliance on incomplete evaluations of recent data contradicting the LNT. It is the time to reconsider the use of the LNT model in LDDR radiation environments. Incorporating the latest science into the regulatory process for risk assessment will (1) ensure science remains the foundation for decision making, (2) reduce unnecessary burdens of costly cleanups, (3) educate the public on the real effects of LDDR radiation exposures, and (4) harmonize government policies with the rest of the radiation scientific community.

Automated detection of radioisotopes from an aircraft platform by pattern recognition analysis of gamma-ray spectra.

A generalized methodology was developed for automating the detection of radioisotopes from gamma-ray spectra collected from an aircraft platform using sodium-iodide detectors. Employing data provided by the U.S Environmental Protection Agency Airborne Spectral Photometric Environmental Collection Technology (ASPECT) program, multivariate classification models based on nonparametric linear discriminant analysis were developed for application to spectra that were preprocessed through a combination of altitude-based scaling and digital filtering. Training sets of spectra for use in building classification models were assembled from a combination of background spectra collected in the field and synthesized spectra obtained by superimposing laboratory-collected spectra of target radioisotopes onto field backgrounds. This approach eliminated the need for field experimentation with radioactive sources for use in building classification models. Through a bi-Gaussian modeling procedure, the discriminant scores that served as the outputs from the classification models were related to associated confidence levels. This provided an easily interpreted result regarding the presence or absence of the signature of a specific radioisotope in each collected spectrum. Through the use of this approach, classifiers were built for cesium-137 (137Cs) and cobalt-60 (60Co), two radioisotopes that are of interest in airborne radiological monitoring applications. The optimized classifiers were tested with field data collected from a set of six geographically diverse sites, three of which contained either 137Cs, 60Co, or both. When the optimized classification models were applied, the overall percentages of correct classifications for spectra collected at these sites were 99.9 and 97.9% for the 60Co and 137Cs classifiers, respectively.

Estimating historical radiation doses to a cohort of U.S. radiologic technologists.

Data have been collected and physical and statistical models have been constructed to estimate unknown occupational radiation doses among 90,000 members of the U.S. Radiologic Technologists cohort who responded to a baseline questionnaire during the mid-1980s. Since the availability of radiation dose data differed by calendar period, different models were developed and applied for years worked before 1960, 1960- 1976 and 1977-1984. The dose estimation used available film-badge measurements (approximately 350,000) for individual cohort members, information provided by the technologists on their work history and protection practices, and measurement and other data derived from the literature. The dosimetry model estimates annual and cumulative occupational badge doses (personal dose equivalent) for each technologist for each year worked from 1916 through 1984 as well as absorbed doses to organs and tissues including bone marrow, female breast, thyroid, ovary, testes, lung and skin. Assumptions have been made about critical variables including average energy of X rays, use of protective aprons, position of film badges, and minimum detectable doses. Uncertainty of badge and organ doses was characterized for each year of each technologist's working career. Monte Carlo methods were used to generate estimates of cumulative organ doses for preliminary cancer risk analyses. The models and predictions presented here, while continuing to be modified and improved, represent one of the most comprehensive dose reconstructions undertaken to date for a large cohort of medical radiation workers.

Assessment of self-help methods to reduce potential exposure to radiological contamination after a large-scale radiological release.

After the release of radioactive materials from a large radiological dispersal device (e.g., dirty bomb), improvised nuclear detonation, or nuclear power plant accident, up to hundreds of square miles may be contaminated. A portion of this area will be evacuated; however, people living in the portion that is not evacuated yet is still contaminated with low-levels of radioactive contamination will be asking for ways they can reduce their exposure. Whether cleaning activities can significantly reduce exposure is not fully understood. In this effort, the ability of cleaning activities to remove cesium (137Cs) was studied. The removal efficacy of cleaning with a commercial product, Simple Green®, was compared to cleaning with water for hard surfaces typically seen in residences. The removal efficacy of laundering fabric material surfaces was also determined for a range of conditions (e.g., fabric material type, wash temperature). During these studies, assessments of the implications of these activities (e.g., cross-contamination, resulting waste streams) were also completed. Simple Green and water were effective for removing 137Cs from plastic laminate and vinyl flooring (93.4-96.8%) but were not effective for removing 137Cs from painted wallboard and wood (7.3-68.1%). It was also determined that there was no significant difference between the two cleaners on all of the surfaces, except plastic laminate, for which Simple Green was slightly more effective. Laundering was effective for removing 137Cs contamination from polyester and cotton swatches and cotton comforters (up to 96.8% in the single swatch testing).

Medical toxicology and public health-update on research and activities at the centers for disease control and prevention and the agency for toxic substances and disease registry.

An extensive review of CDC epidemiological responses to human outbreaks of anthrax from occupational settings between the years of 1950 and 2001 documented a variety of approaches to mitigation and decontamination [2]. These approaches included taking no action, burning contaminated materials, chlorinating water supplies, instituting administrative and engineering controls and PPE, vaccinating potentially exposed individuals, and in 2 instances, fumigating with formaldehyde vapor (now considered to be a human carcinogen). Secondary contamination of a worker's home was documented in 1 case, but not felt to be clinically significant to warrant any decontamination efforts. In response to the B. anthracis attacks in 2001, chlorine dioxide fumigation, vaporous hydrogen peroxide fumigation, and a combination of HEPA vacuuming, cleaning, and bleach application were all techniques used successfully to clean B. anthracis spore contamination.