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1.

HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage.

Landais, Elise; Murrell, Ben; Briney, Bryan; Murrell, Sasha; Rantalainen, Kimmo; Berndsen, Zachary T; Ramos, Alejandra; Wickramasinghe, Lalinda; Smith, Melissa Laird; Eren, Kemal; de Val, Natalia; Wu, Mengyu; Cappelletti, Audrey; Umotoy, Jeffrey; Lie, Yolanda; Wrin, Terri; Algate, Paul; Chan-Hui, Po-Ying; Karita, Etienne; Ward, Andrew B; Wilson, Ian A; Burton, Dennis R; Smith, Davey; Pond, Sergei L Kosakovsky; Poignard, Pascal.

Immunity ; 47(5): 990-1003.e9, 2017 11 21.

Artículo en Inglés | MEDLINE | ID: mdl-29166592

2.

Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers.

Falkowska, Emilia; Le, Khoa M; Ramos, Alejandra; Doores, Katie J; Lee, Jeong Hyun; Blattner, Claudia; Ramirez, Alejandro; Derking, Ronald; van Gils, Marit J; Liang, Chi-Hui; Mcbride, Ryan; von Bredow, Benjamin; Shivatare, Sachin S; Wu, Chung-Yi; Chan-Hui, Po-Ying; Liu, Yan; Feizi, Ten; Zwick, Michael B; Koff, Wayne C; Seaman, Michael S; Swiderek, Kristine; Moore, John P; Evans, David; Paulson, James C; Wong, Chi-Huey; Ward, Andrew B; Wilson, Ian A; Sanders, Rogier W; Poignard, Pascal; Burton, Dennis R.

Immunity ; 40(5): 657-68, 2014 May 15.

Artículo en Inglés | MEDLINE | ID: mdl-24768347

3.

Identification of Human Anti-HIV gp160 Monoclonal Antibodies That Make Effective Immunotoxins.

Pincus, Seth H; Song, Kejing; Maresh, Grace A; Hamer, Dean H; Dimitrov, Dimiter S; Chen, Weizao; Zhang, Mei-Yun; Ghetie, Victor F; Chan-Hui, Po-Ying; Robinson, James E; Vitetta, Ellen S.

J Virol ; 91(3)2017 Feb 01.

Artículo en Inglés | MEDLINE | ID: mdl-27852851

4.

Broad neutralization coverage of HIV by multiple highly potent antibodies.

Walker, Laura M; Huber, Michael; Doores, Katie J; Falkowska, Emilia; Pejchal, Robert; Julien, Jean-Philippe; Wang, Sheng-Kai; Ramos, Alejandra; Chan-Hui, Po-Ying; Moyle, Matthew; Mitcham, Jennifer L; Hammond, Phillip W; Olsen, Ole A; Phung, Pham; Fling, Steven; Wong, Chi-Huey; Phogat, Sanjay; Wrin, Terri; Simek, Melissa D; Koff, Wayne C; Wilson, Ian A; Burton, Dennis R; Poignard, Pascal.

Nature ; 477(7365): 466-70, 2011 Sep 22.

Artículo en Inglés | MEDLINE | ID: mdl-21849977

5.

The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies.

Sok, Devin; Laserson, Uri; Laserson, Jonathan; Liu, Yi; Vigneault, Francois; Julien, Jean-Philippe; Briney, Bryan; Ramos, Alejandra; Saye, Karen F; Le, Khoa; Mahan, Alison; Wang, Shenshen; Kardar, Mehran; Yaari, Gur; Walker, Laura M; Simen, Birgitte B; St John, Elizabeth P; Chan-Hui, Po-Ying; Swiderek, Kristine; Kleinstein, Steven H; Kleinstein, Stephen H; Alter, Galit; Seaman, Michael S; Chakraborty, Arup K; Koller, Daphne; Wilson, Ian A; Church, George M; Burton, Dennis R; Poignard, Pascal.

PLoS Pathog ; 9(11): e1003754, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-24278016

6.

Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo.

Moldt, Brian; Rakasz, Eva G; Schultz, Niccole; Chan-Hui, Po-Ying; Swiderek, Kristine; Weisgrau, Kimberly L; Piaskowski, Shari M; Bergman, Zachary; Watkins, David I; Poignard, Pascal; Burton, Dennis R.

Proc Natl Acad Sci U S A ; 109(46): 18921-5, 2012 Nov 13.

Artículo en Inglés | MEDLINE | ID: mdl-23100539

7.

Human antibodies reveal a protective epitope that is highly conserved among human and nonhuman influenza A viruses.

Grandea, Andres G; Olsen, Ole A; Cox, Thomas C; Renshaw, Mark; Hammond, Philip W; Chan-Hui, Po-Ying; Mitcham, Jennifer L; Cieplak, Witold; Stewart, Shaun M; Grantham, Michael L; Pekosz, Andrew; Kiso, Maki; Shinya, Kyoko; Hatta, Masato; Kawaoka, Yoshihiro; Moyle, Matthew.

Proc Natl Acad Sci U S A ; 107(28): 12658-63, 2010 Jul 13.

Artículo en Inglés | MEDLINE | ID: mdl-20615945

8.

Immunological considerations for developing antibody therapeutics for Influenza A.

Chan-Hui, Po-Ying; Swiderek, Kristine M.

Hum Vaccin Immunother ; 12(2): 474-7, 2016.

Artículo en Inglés | MEDLINE | ID: mdl-26325257

9.

Efficacy of broadly neutralizing monoclonal antibody PG16 in HIV-infected humanized mice.

Stoddart, Cheryl A; Galkina, Sofiya A; Joshi, Pheroze; Kosikova, Galina; Long, Brian R; Maidji, Ekaterina; Moreno, Mary E; Rivera, Jose M; Sanford, Ukina R; Sloan, Barbara; Cieplak, Witold; Wrin, Terri; Chan-Hui, Po-Ying.

Virology ; 462-463: 115-25, 2014 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-24971704

10.

From PGx to molecular diagnostics and personalized medicine.

Chan-Hui, Po-Ying.

Drug Discov Today ; 8(18): 829-31, 2003 Sep 15.

Artículo en Inglés | MEDLINE | ID: mdl-12963318

11.

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target.

Walker, Laura M; Phogat, Sanjay K; Chan-Hui, Po-Ying; Wagner, Denise; Phung, Pham; Goss, Julie L; Wrin, Terri; Simek, Melissa D; Fling, Steven; Mitcham, Jennifer L; Lehrman, Jennifer K; Priddy, Frances H; Olsen, Ole A; Frey, Steven M; Hammond, Phillip W; Kaminsky, Stephen; Zamb, Timothy; Moyle, Matthew; Koff, Wayne C; Poignard, Pascal; Burton, Dennis R.

Science ; 326(5950): 285-9, 2009 Oct 09.

Artículo en Inglés | MEDLINE | ID: mdl-19729618

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