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1.

CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels.

Tanzo, Julia T; Li, Veronica L; Wiggenhorn, Amanda L; Moya-Garzon, Maria Dolores; Wei, Wei; Lyu, Xuchao; Dong, Wentao; Tahir, Usman A; Chen, Zsu-Zsu; Cruz, Daniel E; Deng, Shuliang; Shi, Xu; Zheng, Shuning; Guo, Yan; Sims, Mario; Abu-Remaileh, Monther; Wilson, James G; Gerszten, Robert E; Long, Jonathan Z; Benson, Mark D.

J Biol Chem ; 299(6): 104764, 2023 06.

Artículo en Inglés | MEDLINE | ID: mdl-37121548

2.

Whole Genome Sequence Analysis of the Plasma Proteome in Black Adults Provides Novel Insights Into Cardiovascular Disease.

Katz, Daniel H; Tahir, Usman A; Bick, Alexander G; Pampana, Akhil; Ngo, Debby; Benson, Mark D; Yu, Zhi; Robbins, Jeremy M; Chen, Zsu-Zsu; Cruz, Daniel E; Deng, Shuliang; Farrell, Laurie; Sinha, Sumita; Schmaier, Alec A; Shen, Dongxiao; Gao, Yan; Hall, Michael E; Correa, Adolfo; Tracy, Russell P; Durda, Peter; Taylor, Kent D; Liu, Yongmei; Johnson, W Craig; Guo, Xiuqing; Yao, Jie; Ida Chen, Yii-Der; Manichaikul, Ani W; Jain, Deepti; Bouchard, Claude; Sarzynski, Mark A; Rich, Stephen S; Rotter, Jerome I; Wang, Thomas J; Wilson, James G; Natarajan, Pradeep; Gerszten, Robert E.

Circulation ; 145(5): 357-370, 2022 02.

Artículo en Inglés | MEDLINE | ID: mdl-34814699

3.

Stability and reproducibility of proteomic profiles in epidemiological studies: comparing the Olink and SOMAscan platforms.

Haslam, Danielle E; Li, Jun; Dillon, Simon T; Gu, Xuesong; Cao, Yin; Zeleznik, Oana A; Sasamoto, Naoko; Zhang, Xuehong; Eliassen, A Heather; Liang, Liming; Stampfer, Meir J; Mora, Samia; Chen, Zsu-Zsu; Terry, Kathryn L; Gerszten, Robert E; Hu, Frank B; Chan, Andrew T; Libermann, Towia A; Bhupathiraju, Shilpa N.

Proteomics ; 22(13-14): e2100170, 2022 07.

Artículo en Inglés | MEDLINE | ID: mdl-35598103

4.

Metabolomics and Proteomics in Type 2 Diabetes.

Chen, Zsu-Zsu; Gerszten, Robert E.

Circ Res ; 126(11): 1613-1627, 2020 05 22.

Artículo en Inglés | MEDLINE | ID: mdl-32437301

5.

Predictors of Mortality in Hypercalcemia of Advanced Chronic Liver Disease.

Majety, Priyanka; Groysman, Anna; Erlikh, Natanie; Chen, Zsu Zsu; Westcott, Gregory P.

Endocr Pract ; 28(10): 1062-1068, 2022 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-35868607

6.

Understanding Myocardial Metabolism in the Context of Cardio-Oncology.

Liu, Jing; Chen, Zsu-Zsu; Patel, Jagvi; Asnani, Aarti.

Heart Fail Clin ; 18(3): 415-424, 2022 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-35718416

7.

Genetic deletion of gpr27 alters acylcarnitine metabolism, insulin sensitivity, and glucose homeostasis in zebrafish.

Nath, Anjali K; Ma, Junyan; Chen, Zsu-Zsu; Li, Zhuyun; Vitery, Maria Del Carmen; Kelley, Michelle L; Peterson, Randall T; Gerszten, Robert E; Yeh, Jing-Ruey J.

FASEB J ; 34(1): 1546-1557, 2020 01.

Artículo en Inglés | MEDLINE | ID: mdl-31914600

8.

A parametric bootstrap approach for computing confidence intervals for genetic correlations with application to genetically-determined protein-protein networks.

Tsai, Yi-Ting; Hrytsenko, Yana; Elgart, Michael; Usman, Tahir; Chen, Zsu-Zsu; Wilson, James G; Gerszten, Robert; Sofer, Tamar.

HGG Adv ; : 100304, 2024 May 07.

Artículo en Inglés | MEDLINE | ID: mdl-38720460

9.

Lac-Phe mediates the effects of metformin on food intake and body weight.

Xiao, Shuke; Li, Veronica L; Lyu, Xuchao; Chen, Xudong; Wei, Wei; Abbasi, Fahim; Knowles, Joshua W; Tung, Alan Sheng-Hwa; Deng, Shuliang; Tiwari, Gaurav; Shi, Xu; Zheng, Shuning; Farrell, Laurie; Chen, Zsu-Zsu; Taylor, Kent D; Guo, Xiuqing; Goodarzi, Mark O; Wood, Alexis C; Chen, Yii-Der Ida; Lange, Leslie A; Rich, Stephen S; Rotter, Jerome I; Clish, Clary B; Tahir, Usman A; Gerszten, Robert E; Benson, Mark D; Long, Jonathan Z.

Nat Metab ; 6(4): 659-669, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-38499766

10.

Massive Thymic Hyperplasia Masquerading as Cancer: A Case Report and Review of the Literature.

Gatof, Emily Stern; Jassim, Sarmad H; Ahn, Leah; Chen, Zsu-Zsu; VanderLaan, Paul A; Rangachari, Deepa.

JTO Clin Res Rep ; 4(2): 100463, 2023 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-36846571

11.

Surface Electrical Impedance Myography Detects Skeletal Muscle Atrophy in Aged Wildtype Zebrafish and Aged gpr27 Knockout Zebrafish.

Rutkove, Seward B; Chen, Zsu-Zsu; Pandeya, Sarbesh; Callegari, Santiago; Mourey, Tyler; Nagy, Janice A; Nath, Anjali K.

Biomedicines ; 11(7)2023 Jul 07.

Artículo en Inglés | MEDLINE | ID: mdl-37509577

12.

A parametric bootstrap approach for computing confidence intervals for genetic correlations with application to genetically-determined protein-protein networks.

Tsai, Yi-Ting; Hrytsenko, Yana; Elgart, Michael; Tahir, Usman; Chen, Zsu-Zsu; Wilson, James G; Gerszten, Robert; Sofer, Tamar.

medRxiv ; 2023 Oct 25.

Artículo en Inglés | MEDLINE | ID: mdl-37961678

13.

Protein Markers of Diabetes Discovered in an African American Cohort.

Chen, Zsu-Zsu; Gao, Yan; Keyes, Michelle J; Deng, Shuliang; Mi, Michael; Farrell, Laurie A; Shen, Dongxiao; Tahir, Usman A; Cruz, Daniel E; Ngo, Debby; Benson, Mark D; Robbins, Jeremy M; Correa, Adolfo; Wilson, James G; Gerszten, Robert E.

Diabetes ; 72(4): 532-543, 2023 04 01.

Artículo en Inglés | MEDLINE | ID: mdl-36630488

14.

Mixed meal tolerance testing highlights in diabetes altered branched-chain ketoacid metabolism and pathways associated with all-cause mortality.

Mi, Michael Y; Whitlock, Mark; Shi, Xu; Farrell, Laurie A; Bhambhani, Victoria M; Quadir, Juweria; Blatnik, Matthew; Wald, Kyle P; Tierney, Brendan; Kim, Albert; Loudon, Peter; Chen, Zsu-Zsu; Correa, Adolfo; Gao, Yan; Carson, April P; Bertoni, Alain G; Roth Flach, Rachel J; Gerszten, Robert E.

Am J Clin Nutr ; 117(3): 529-539, 2023 03.

Artículo en Inglés | MEDLINE | ID: mdl-36811472

15.

CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels.

Tanzo, Julia T; Li, Veronica L; Wiggenhorn, Amanda L; Moya-Garzon, Maria Dolores; Wei, Wei; Lyu, Xuchao; Dong, Wentao; Tahir, Usman A; Chen, Zsu-Zsu; Cruz, Daniel E; Deng, Shuliang; Shi, Xu; Zheng, Shuning; Guo, Yan; Sims, Mario; Abu-Remaileh, Monther; Wilson, James G; Gerszten, Robert E; Long, Jonathan Z; Benson, Mark D.

bioRxiv ; 2023 Mar 09.

Artículo en Inglés | MEDLINE | ID: mdl-36945562

16.

Lac-Phe mediates the anti-obesity effect of metformin.

Xiao, Shuke; Li, Veronica L; Lyu, Xuchao; Chen, Xudong; Wei, Wei; Abbasi, Fahim; Knowles, Joshua W; Deng, Shuliang; Tiwari, Gaurav; Shi, Xu; Zheng, Shuning; Farrell, Laurie; Chen, Zsu-Zsu; Taylor, Kent D; Guo, Xiuqing; Goodarzi, Mark O; Wood, Alexis C; Ida Chen, Yii-Der; Lange, Leslie A; Rich, Stephen S; Rotter, Jerome I; Clish, Clary B; Tahir, Usman A; Gerszten, Robert E; Benson, Mark D; Long, Jonathan Z.

bioRxiv ; 2023 Nov 04.

Artículo en Inglés | MEDLINE | ID: mdl-37961394

17.

Protein-metabolite association studies identify novel proteomic determinants of metabolite levels in human plasma.

Benson, Mark D; Eisman, Aaron S; Tahir, Usman A; Katz, Daniel H; Deng, Shuliang; Ngo, Debby; Robbins, Jeremy M; Hofmann, Alissa; Shi, Xu; Zheng, Shuning; Keyes, Michelle; Yu, Zhi; Gao, Yan; Farrell, Laurie; Shen, Dongxiao; Chen, Zsu-Zsu; Cruz, Daniel E; Sims, Mario; Correa, Adolfo; Tracy, Russell P; Durda, Peter; Taylor, Kent D; Liu, Yongmei; Johnson, W Craig; Guo, Xiuqing; Yao, Jie; Chen, Yii-Der Ida; Manichaikul, Ani W; Jain, Deepti; Yang, Qiong; Bouchard, Claude; Sarzynski, Mark A; Rich, Stephen S; Rotter, Jerome I; Wang, Thomas J; Wilson, James G; Clish, Clary B; Sarkar, Indra Neil; Natarajan, Pradeep; Gerszten, Robert E.

Cell Metab ; 35(9): 1646-1660.e3, 2023 09 05.

Artículo en Inglés | MEDLINE | ID: mdl-37582364

18.

Plasma metabolomic signatures of obesity and risk of type 2 diabetes.

Pan, Xiong-Fei; Chen, Zsu-Zsu; Wang, Thomas J; Shu, Xiang; Cai, Hui; Cai, Qiuyin; Clish, Clary B; Shi, Xu; Zheng, Wei; Gerszten, Robert E; Shu, Xiao-Ou; Yu, Danxia.

Obesity (Silver Spring) ; 30(11): 2294-2306, 2022 11.

Artículo en Inglés | MEDLINE | ID: mdl-36161775

19.

Proteomic profiling platforms head to head: Leveraging genetics and clinical traits to compare aptamer- and antibody-based methods.

Katz, Daniel H; Robbins, Jeremy M; Deng, Shuliang; Tahir, Usman A; Bick, Alexander G; Pampana, Akhil; Yu, Zhi; Ngo, Debby; Benson, Mark D; Chen, Zsu-Zsu; Cruz, Daniel E; Shen, Dongxiao; Gao, Yan; Bouchard, Claude; Sarzynski, Mark A; Correa, Adolfo; Natarajan, Pradeep; Wilson, James G; Gerszten, Robert E.

Sci Adv ; 8(33): eabm5164, 2022 08 19.

Artículo en Inglés | MEDLINE | ID: mdl-35984888

20.

Metabolomic Analysis of Coronary Heart Disease in an African American Cohort From the Jackson Heart Study.

Cruz, Daniel E; Tahir, Usman A; Hu, Jie; Ngo, Debby; Chen, Zsu-Zsu; Robbins, Jeremy M; Katz, Daniel; Balasubramanian, Raji; Peterson, Bennet; Deng, Shuliang; Benson, Mark D; Shi, Xu; Dailey, Lucas; Gao, Yan; Correa, Adolfo; Wang, Thomas J; Clish, Clary B; Rexrode, Kathryn M; Wilson, James G; Gerszten, Robert E.

JAMA Cardiol ; 7(2): 184-194, 2022 02 01.

Artículo en Inglés | MEDLINE | ID: mdl-34851361

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CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels.

Whole Genome Sequence Analysis of the Plasma Proteome in Black Adults Provides Novel Insights Into Cardiovascular Disease.

Stability and reproducibility of proteomic profiles in epidemiological studies: comparing the Olink and SOMAscan platforms.

Metabolomics and Proteomics in Type 2 Diabetes.

Predictors of Mortality in Hypercalcemia of Advanced Chronic Liver Disease.

Understanding Myocardial Metabolism in the Context of Cardio-Oncology.

Genetic deletion of gpr27 alters acylcarnitine metabolism, insulin sensitivity, and glucose homeostasis in zebrafish.

A parametric bootstrap approach for computing confidence intervals for genetic correlations with application to genetically-determined protein-protein networks.

Lac-Phe mediates the effects of metformin on food intake and body weight.

Massive Thymic Hyperplasia Masquerading as Cancer: A Case Report and Review of the Literature.

Surface Electrical Impedance Myography Detects Skeletal Muscle Atrophy in Aged Wildtype Zebrafish and Aged gpr27 Knockout Zebrafish.

A parametric bootstrap approach for computing confidence intervals for genetic correlations with application to genetically-determined protein-protein networks.

Protein Markers of Diabetes Discovered in an African American Cohort.

Mixed meal tolerance testing highlights in diabetes altered branched-chain ketoacid metabolism and pathways associated with all-cause mortality.

CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels.

Lac-Phe mediates the anti-obesity effect of metformin.

Protein-metabolite association studies identify novel proteomic determinants of metabolite levels in human plasma.

Plasma metabolomic signatures of obesity and risk of type 2 diabetes.

Proteomic profiling platforms head to head: Leveraging genetics and clinical traits to compare aptamer- and antibody-based methods.

Metabolomic Analysis of Coronary Heart Disease in an African American Cohort From the Jackson Heart Study.