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1.

Exploration of O-GlcNAc transferase glycosylation sites reveals a target sequence compositional bias.

Chong, P Andrew; Nosella, Michael L; Vanama, Manasvi; Ruiz-Arduengo, Roxana; Forman-Kay, Julie D.

J Biol Chem ; 299(5): 104629, 2023 05.

Artículo en Inglés | MEDLINE | ID: mdl-36963488

2.

Pseudomonas aeruginosa AlgF is a protein-protein interaction mediator required for acetylation of the alginate exopolysaccharide.

Low, Kristin E; Gheorghita, Andreea A; Tammam, Stephanie D; Whitfield, Gregory B; Li, Yancheng E; Riley, Laura M; Weadge, Joel T; Caldwell, Shane J; Chong, P Andrew; Walvoort, Marthe T C; Kitova, Elena N; Klassen, John S; Codée, Jeroen D C; Howell, P Lynne.

J Biol Chem ; 299(11): 105314, 2023 11.

Artículo en Inglés | MEDLINE | ID: mdl-37797696

3.

O-Linked-N-Acetylglucosaminylation of the RNA-Binding Protein EWS N-Terminal Low Complexity Region Reduces Phase Separation and Enhances Condensate Dynamics.

Nosella, Michael L; Tereshchenko, Maria; Pritisanac, Iva; Chong, P Andrew; Toretsky, Jeffrey A; Lee, Hyun O; Forman-Kay, Julie D.

J Am Chem Soc ; 143(30): 11520-11534, 2021 08 04.

Artículo en Inglés | MEDLINE | ID: mdl-34304571

4.

Stabilization of a nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator yields insight into disease-causing mutations.

Vernon, Robert M; Chong, P Andrew; Lin, Hong; Yang, Zhengrong; Zhou, Qingxian; Aleksandrov, Andrei A; Dawson, Jennifer E; Riordan, John R; Brouillette, Christie G; Thibodeau, Patrick H; Forman-Kay, Julie D.

J Biol Chem ; 292(34): 14147-14164, 2017 08 25.

Artículo en Inglés | MEDLINE | ID: mdl-28655774

5.

Molecular biology: A hidden competitive advantage of disorder.

Chong, P Andrew; Forman-Kay, Julie D.

Nature ; 543(7645): 325-326, 2017 03 16.

Artículo en Inglés | MEDLINE | ID: mdl-28273062

6.

Direct Binding of the Corrector VX-809 to Human CFTR NBD1: Evidence of an Allosteric Coupling between the Binding Site and the NBD1:CL4 Interface.

Hudson, Rhea P; Dawson, Jennifer E; Chong, P Andrew; Yang, Zhengrong; Millen, Linda; Thomas, Philip J; Brouillette, Christie G; Forman-Kay, Julie D.

Mol Pharmacol ; 92(2): 124-135, 2017 08.

Artículo en Inglés | MEDLINE | ID: mdl-28546419

7.

Deletion of Phenylalanine 508 in the First Nucleotide-binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator Increases Conformational Exchange and Inhibits Dimerization.

Chong, P Andrew; Farber, Patrick J; Vernon, Robert M; Hudson, Rhea P; Mittermaier, Anthony K; Forman-Kay, Julie D.

J Biol Chem ; 290(38): 22862-78, 2015 Sep 18.

Artículo en Inglés | MEDLINE | ID: mdl-26149808

8.

Oxidative Inhibition of Pbp1 Phase Separation.

Chong, P Andrew; Forman-Kay, Julie D.

Biochemistry ; 58(28): 3057-3059, 2019 07 16.

Artículo en Inglés | MEDLINE | ID: mdl-31282150

9.

Conformational changes relevant to channel activity and folding within the first nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator.

Hudson, Rhea P; Chong, P Andrew; Protasevich, Irina I; Vernon, Robert; Noy, Efrat; Bihler, Hermann; An, Jian Li; Kalid, Ori; Sela-Culang, Inbal; Mense, Martin; Senderowitz, Hanoch; Brouillette, Christie G; Forman-Kay, Julie D.

J Biol Chem ; 287(34): 28480-94, 2012 Aug 17.

Artículo en Inglés | MEDLINE | ID: mdl-22722932

10.

Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity.

Chong, P Andrew; Lin, Hong; Wrana, Jeffrey L; Forman-Kay, Julie D.

Proc Natl Acad Sci U S A ; 107(43): 18404-9, 2010 Oct 26.

Artículo en Inglés | MEDLINE | ID: mdl-20937913

11.

Characterization of the PilN, PilO and PilP type IVa pilus subcomplex.

Tammam, S; Sampaleanu, L M; Koo, J; Sundaram, P; Ayers, M; Chong, P Andrew; Forman-Kay, J D; Burrows, L L; Howell, P L.

Mol Microbiol ; 82(6): 1496-514, 2011 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-22053789

12.

FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation.

Birsa, Nicol; Ule, Agnieszka M; Garone, Maria Giovanna; Tsang, Brian; Mattedi, Francesca; Chong, P Andrew; Humphrey, Jack; Jarvis, Seth; Pisiren, Melis; Wilkins, Oscar G; Nosella, Micheal L; Devoy, Anny; Bodo, Cristian; de la Fuente, Rafaela Fernandez; Fisher, Elizabeth M C; Rosa, Alessandro; Viero, Gabriella; Forman-Kay, Julie D; Schiavo, Giampietro; Fratta, Pietro.

Sci Adv ; 7(30)2021 07.

Artículo en Inglés | MEDLINE | ID: mdl-34290090

13.

Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p.

Stollar, Elliott J; Garcia, Bianca; Chong, P Andrew; Rath, Arianna; Lin, Hong; Forman-Kay, Julie D; Davidson, Alan R.

J Biol Chem ; 284(39): 26918-27, 2009 Sep 25.

Artículo en Inglés | MEDLINE | ID: mdl-19590096

14.

Non-cooperative 4E-BP2 folding with exchange between eIF4E-binding and binding-incompatible states tunes cap-dependent translation inhibition.

Dawson, Jennifer E; Bah, Alaji; Zhang, Zhenfu; Vernon, Robert M; Lin, Hong; Chong, P Andrew; Vanama, Manasvi; Sonenberg, Nahum; Gradinaru, Claudiu C; Forman-Kay, Julie D.

Nat Commun ; 11(1): 3146, 2020 06 19.

Artículo en Inglés | MEDLINE | ID: mdl-32561718

15.

CFTR structure.

Callebaut, Isabelle; Chong, P Andrew; Forman-Kay, Julie D.

J Cyst Fibros ; 17(2S): S5-S8, 2018 03.

Artículo en Inglés | MEDLINE | ID: mdl-28866450

16.

RGG/RG Motif Regions in RNA Binding and Phase Separation.

Chong, P Andrew; Vernon, Robert M; Forman-Kay, Julie D.

J Mol Biol ; 430(23): 4650-4665, 2018 11 02.

Artículo en Inglés | MEDLINE | ID: mdl-29913160

17.

Interplay of buried histidine protonation and protein stability in prion misfolding.

Malevanets, Anatoly; Chong, P Andrew; Hansen, D Flemming; Rizk, Paul; Sun, Yulong; Lin, Hong; Muhandiram, Ranjith; Chakrabartty, Avi; Kay, Lewis E; Forman-Kay, Julie D; Wodak, Shoshana J.

Sci Rep ; 7(1): 882, 2017 04 13.

Artículo en Inglés | MEDLINE | ID: mdl-28408762

18.

Liquid-liquid phase separation in cellular signaling systems.

Chong, P Andrew; Forman-Kay, Julie D.

Curr Opin Struct Biol ; 41: 180-186, 2016 12.

Artículo en Inglés | MEDLINE | ID: mdl-27552079

19.

A New Phase in ALS Research.

Chong, P Andrew; Forman-Kay, Julie D.

Structure ; 24(9): 1435-6, 2016 09 06.

Artículo en Inglés | MEDLINE | ID: mdl-27602988

20.

Binding screen for cystic fibrosis transmembrane conductance regulator correctors finds new chemical matter and yields insights into cystic fibrosis therapeutic strategy.

Hall, Justin D; Wang, Hong; Byrnes, Laura J; Shanker, Suman; Wang, Kelong; Efremov, Ivan V; Chong, P Andrew; Forman-Kay, Julie D; Aulabaugh, Ann E.

Protein Sci ; 25(2): 360-73, 2016 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-26444971

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Exploration of O-GlcNAc transferase glycosylation sites reveals a target sequence compositional bias.

Pseudomonas aeruginosa AlgF is a protein-protein interaction mediator required for acetylation of the alginate exopolysaccharide.

O-Linked-N-Acetylglucosaminylation of the RNA-Binding Protein EWS N-Terminal Low Complexity Region Reduces Phase Separation and Enhances Condensate Dynamics.

Stabilization of a nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator yields insight into disease-causing mutations.

Molecular biology: A hidden competitive advantage of disorder.

Direct Binding of the Corrector VX-809 to Human CFTR NBD1: Evidence of an Allosteric Coupling between the Binding Site and the NBD1:CL4 Interface.

Deletion of Phenylalanine 508 in the First Nucleotide-binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator Increases Conformational Exchange and Inhibits Dimerization.

Oxidative Inhibition of Pbp1 Phase Separation.

Conformational changes relevant to channel activity and folding within the first nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator.

Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity.

Characterization of the PilN, PilO and PilP type IVa pilus subcomplex.

FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation.

Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p.

Non-cooperative 4E-BP2 folding with exchange between eIF4E-binding and binding-incompatible states tunes cap-dependent translation inhibition.

CFTR structure.

RGG/RG Motif Regions in RNA Binding and Phase Separation.

Interplay of buried histidine protonation and protein stability in prion misfolding.

Liquid-liquid phase separation in cellular signaling systems.

A New Phase in ALS Research.

Binding screen for cystic fibrosis transmembrane conductance regulator correctors finds new chemical matter and yields insights into cystic fibrosis therapeutic strategy.