RESUMEN
This case was the subject of a Grand Round Presentation at the Royal Marsden Hospital, Sutton, UK on 8 June 2004. A case of metachronous, bilateral testicular germ-cell tumours (TGCTs) arising in a patient with a family history of this disease was presented. The second primary was managed conservatively. The rationale and outcome of this approach was presented, along with a discussion of the management of early stage TGCTs and the genetics of familial and bilateral disease.
Asunto(s)
Germinoma/terapia , Neoplasias Primarias Secundarias/terapia , Neoplasias Testiculares/terapia , Adulto , Terapia Combinada , Germinoma/patología , Humanos , Masculino , Estadificación de Neoplasias , Neoplasias Primarias Secundarias/patología , Neoplasias Testiculares/patologíaRESUMEN
Central nervous system (CNS) presentation of adult T-cell lymphoma/leukaemia is rare, and almost invariably associated with systemic disease. We report an unusual manifestation of adult T-cell lymphoma/leukaemia, with isolated CNS involvement and unusual imaging findings. We also describe objective response to antiviral therapy. To our knowledge, this is the first report of such presentation and response.