RESUMEN
OBJECTIVES: To investigate the changes of respiratory function in patients affected by chronic obstructive pulmonary disease (COPD) with single dorsal osteoporotic vertebral compression fractures (OVCFs) treated with vertebroplasty (VTP). METHODS: Forty-five patients affected by COPD and single dorsal OVCF underwent VTP (29 men, 16 women; mean age 71.4 years, range 65-77 years). Inclusion criteria were magnetic resonance findings of bone marrow oedema, without intracanal bone fragments and refractory pain to medical treatment for at least 3 months. Osteoporosis was assessed by bone densitometry. Spirometry was performed before and after treatment. RESULTS: A significant VAS-score decrease was observed 1 week after VTP, with a subsequent decrease over time; vital capacity (VC) and forced vital capacity (FVC) improved over time, reaching a plateau at 3 months. Forced expiratory volume at 1 s (FEV1) did not significantly differ between the pre-VTP values and follow-up values. A significant correlation was observed between VAS-score values and VC, and VAS-score values and FVC. No significant correlation was observed between VAS-score values and FEV1 values. CONCLUSIONS: VTP improves restrictive ventilatory impairment in patients with moderate and severe COPD affected by single thoracic OVCFs. We recommend this treatment in the management of these patients. KEY POINTS: ⢠Osteoporosis is a major comorbidity in chronic obstructive pulmonary disease (COPD) patients. ⢠Pain due to osteoporotic vertebral compression fractures worsens respiratory failure in COPD. ⢠Vertebroplasty improves ventilatory impairment in COPD patients with osteoporotic vertebral compression fractures.
Asunto(s)
Fracturas por Compresión/cirugía , Fracturas Osteoporóticas/cirugía , Enfermedad Pulmonar Obstructiva Crónica/fisiopatología , Recuperación de la Función , Fracturas de la Columna Vertebral/cirugía , Vértebras Torácicas/lesiones , Vertebroplastia/métodos , Anciano , Femenino , Fluoroscopía , Estudios de Seguimiento , Fracturas por Compresión/complicaciones , Fracturas por Compresión/diagnóstico , Humanos , Imagen por Resonancia Magnética , Masculino , Fracturas Osteoporóticas/complicaciones , Fracturas Osteoporóticas/diagnóstico , Enfermedad Pulmonar Obstructiva Crónica/complicaciones , Pruebas de Función Respiratoria , Fenómenos Fisiológicos Respiratorios , Fracturas de la Columna Vertebral/complicaciones , Fracturas de la Columna Vertebral/diagnóstico , Cirugía Asistida por Computador/métodos , Vértebras Torácicas/diagnóstico por imagen , Vértebras Torácicas/patología , Factores de Tiempo , Resultado del TratamientoRESUMEN
Well-differentiated retroperitoneal liposarcomas are slow growing and low-grade tumors, reaching usually huge size before being symptomatic and so diagnosed, therefore with increase of the surgical risk and of the probability of dedifferentiation. Inguinal location of these tumors is unusual and rarely diagnosed.
RESUMEN
Malignant peripheral nerve sheath tumour (MPNST) is extremely rare malignancy in the general population, occurring more frequently in patients with Neurofibromatosis type 1 (NF1). In the literature five cases of MPNST arising from the parapharyngeal space (PPS) in patients without neurofibromatosis have been reported. We report imaging techniques in a patient with MPNST in the PPS, who had neither a family history nor sign of NF1. Computed tomography (CT) scan and magnetic resonance imaging (MRI) were performed for a correct therapeutic planning. CT and MRI findings were correlated with hystopathological diagnosis.